Abstract
Acetanilide derivatives, 2,2′-thiobis[N-(4-nitrophenyl)acetamide] and 2,2′-thiobis[N-(4-chlorophenyl)acetamide], were synthesized and characterized. They were shown to cause a considerable oxidative stress in rats.
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Abbreviations
- MDA:
-
malondialdehide
REFERENCES
Isaeva, G.A., Dmitriev, A.V., and Isaev, P.P., Rus. J.Phys. Chem., 2001, vol. 75, pp. 1716–1719.
Pernerstorfer, T., Schmid, R., Bieglmayer, C., Eichler, H.G., Kapiotis, S., and Jilma, B., Clin. Pharmacol. Ther., 2000, vol. 67, pp. 70–71.
Vargas, R., Maneatis, T., Bynum, L., Peterson, C., and McMahon, F.G., J. Clin. Pharmacol., 1994, vol. 34, pp. 848–853.
Roche, J.J., Cisneros, G.J., and Acs, G., Angle Orthod., 1997, vol. 67, pp. 231–236.
Peterson, J.M., Trappe, T.A., Mylona, E., White, F., Lambert, C.P., Evans, W.J., and Pizza, F.X., Med. Sci. Sports Exerc., 2003, vol. 35, pp. 892–896.
Moore, P.K. and Marshall, M., Dig. Liver Dis., 2003, vol. 35, pp. 49–60.
Ye, C.M., Wang, X.J., and Zheng, H.H., J. Environ. Sci. (China), 2002, vol. 14, pp. 492–524.
Lacey, J.V., Sherman, M.E., Hartge, P., Schatzkin, A., and Schairer, C., Int. J. Cancer, 2004, vol. 108, pp. 281–286.
Viitanen, H., Tuominen, N., Vaaraniemi, H., Nikanne, E., and Annila, P., Br. J. Anaesth., 2003, vol. 91, pp. 363–367.
Diener, H.C. and Limmroth, V., Curr. Med. Res. Opin., 2001, vol. 17, pp. 13–16.
Brune, K., Agents Actions Suppl., 1988, vol. 25, pp. 9–19.
Dowdy, J., Brower, S., and Miller, M.R., Toxicol. Sci., 2003, vol. 72, pp. 57–65.
Chaturvedi, B., Tiwari, N., and Nizamuddin, Indian J.Chem., 1989, vol. 28, pp. 358–361.
Miyahara, Y., Inazu, T., and Yoshino, T., Bull. Chem. Soc. Japan, 1980, vol. 53, pp. 1187–1188.
Koparr, M., Cansz, A., Ahmedzade, M., and Cetin, A., Heteroat. Chem., 2004, vol. 15, pp. 26–31.
Jain, S.K. and Levine, S.N., Free Radical Biol. Med., 1995, vol. 18, pp. 337–341.
Blazka, M.E., Elwell, M.R., Holladay, S.D., Wilson, R.E., and Luster, M.I., Toxicol. Pathol., 1996, vol. 24, pp. 181–189.
Bromer, M.Q. and Black, M., Clin. Liver Dis., 2003, vol. 7, pp. 351–367.
Hattori, A., Yamada, N., Nishikawa, T., Fukuda, H., and Fujino, T., Biosci. Biotechnol. Biochem., 2001, vol. 65, pp. 2555–2557.
Kozer, E., Evans, S., Barr, J., Greenberg, R., Soriano, I., Bulkowstein, M., Petrov, I., Chen-Levi, Z., Barzilay, B., and Berkovitch, M., Br. J. Clin. Pharmacol., 2003, vol. 55, pp. 234–240.
Suhail, M. and Ahmad, I., Indian J. Exp. Biol., 1995, vol. 33, pp. 269–271.
Kapiotis, S., Sengoelge, G., Hermann, M., Held, I., Seelos, C., and Gmeiner, B.M., Arterioscler. Thromb. Vasc. Biol., 1997, vol. 17, pp. 2855–2860.
Catignani, G.L. and Bieri, J.G., Clin. Chem. (Washington D.C.), 1983, vol. 29, pp. 708–712.
Miller, K.W., Lorr, N.A., and Yang, C.S., Anal. Biochem., 1984, vol. 138, pp. 340–345.
Cerhata, D., Bauerova, A., and Ginter, B., Caska Slov. Farm., 1994, vol. 43, pp. 166–168.
Tavazzi, B., Lazzarino, G., Di-Piero, D., and Giardina, B., Free Radical Biol. Med., 1992, vol. 13, pp. 75–78.
Karatas, F., Karatepe, M., and Baysar, A., Anal. Biochem., 2002, vol. 311, pp. 76–79.
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Translated from Bioorganicheskaya Khimiya, Vol. 31, No. 5, 2005, pp. 553–556.
Original Russian Text Copyright © 2005 by Karatas, Cansiz, Kara, Karatepe, Koparir.
The text was submitted by the authors in English.
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Karatas, F., Cansiz, A., Kara, H. et al. Synthesis of Two New Acetanilide Derivatives and Their Effect on the Serum Antioxidant Vitamins (A, E, and C) and the MDA Level in Rats. Russ J Bioorg Chem 31, 499–501 (2005). https://doi.org/10.1007/s11171-005-0068-7
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DOI: https://doi.org/10.1007/s11171-005-0068-7