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A novel synthesis of 2,5-diphenylpyrazine

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Abstract

The compound C16H12N2 (2,5-diphenylpyrazine) was obtained as the by-product of synthesizing 5H-Imidazol[2,3-b]isoquinoline-1-ethanol-5-one,1,2,3,10b-tetrahydro-, β(S)-phenyl-3(S)-phenyl-(compound 2), and its structure was determined by X-ray diffraction. The crystal is monoclinic, P2(1)/c, a = 13.466(5) Å, α = 90.00º, b = 5.758(2) Å, β = 93.049(9)º, c = 7.713(3) Å, γ = 90.00º, V = 597.2(4) Å3, Z = 2, Dcalc. = 1.292 mg/m3; the final R factor is R1 = 0.0592, 771 for reflections with I 0 > 2σ(I 0).

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References

  1. A.E. Erickson, P.E. Spoerri, J. Am. Chem. Soc. 68, 400–402 (1946)

    Article  CAS  Google Scholar 

  2. C. Charalambos, N. Sotirios, C. Panayotis, J. Chem. Eng. Data 32, 478–479 (1987)

    Article  Google Scholar 

  3. B.M. Latha, V. Sadasivam, B. Sivasankar, Catal. Commun. 8, 1070–1073 (2007)

    Article  CAS  Google Scholar 

  4. J. Albaneze-Walker, M. Zhao, M.D. Baker, P.G. Dormer, J. McNamara, Tetrahedron Lett. 43, 6747–6750 (2002)

    Article  CAS  Google Scholar 

  5. B. George, G. Jose, J. Org. Chem. 56, 2605–2606 (1991)

    Article  Google Scholar 

  6. H. Alper, S. Wollowitz, J. Am. Chem. Soc. 97, 3541–3543 (1975)

    Article  CAS  Google Scholar 

  7. J. Daniel, D.N. Dhar, Synth. Commun. 23, 2151–2157 (1993)

    Article  CAS  Google Scholar 

  8. Sheldrick, G. M. SHELXS-97, Program for X-ray Crystal Structure Solution (Göttingen University, Germany, 1997)

  9. Sheldrick, G. M. SHELXL-97, Program for X-ray Crystal Structure Refinement (Göttingen University, Germany, 1997)

  10. G.H. Stout, L.H. Jensen, X-Ray Structure Determination: A Practical Guide (MacMillan, New York, 1968)

    Google Scholar 

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Authors and Affiliations

  1. Hefei University of Technology, Hefei, 230009, China

    Mei Luo

  2. University of Science and Technology of China, Hefei, 230009, China

    Wen Min Pang, Hao Yin & Ke Liang Hu

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  1. Mei Luo
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  2. Wen Min Pang
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  3. Hao Yin
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  4. Ke Liang Hu
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Correspondence to Mei Luo.

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Luo, M., Pang, W.M., Yin, H. et al. A novel synthesis of 2,5-diphenylpyrazine. Res Chem Intermed 36, 491–494 (2010). https://doi.org/10.1007/s11164-010-0159-9

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  • DOI: https://doi.org/10.1007/s11164-010-0159-9

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