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Phenolic sucrose esters: evolution, regulation, biosynthesis, and biological functions

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Abstract

Phenolic sucrose esters (PSEs) are a diverse group of specialized metabolites that are present in several angiosperm lineages. Phylogenetic reconstruction and structural variation suggest that these metabolites may have evolved independently in monocots and dicots. Constitutive variation in PSE abundance across plant organs and developmental stages is correlated with transcriptional regulation of the upstream phenylpropanoid pathway, whereas pathogen induction is regulated by stress-related phytohormones such as ethylene. Shared structural features of PSEs indicate that their biosynthesis may involve one or more hydroxycinnamoyl transferases and BAHD acetyltransferases, which could be identified by correlative analyses of multi-omics datasets. Elucidation of the core biosynthetic pathway of PSEs will be essential for more detailed studies of the biological function of these compounds and their potential medicinal and agricultural applications.

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Acknowledgements

This work was supported by the Youth Program of National Natural Science Foundation of China (Award 32000229 to S.Z.), Shenzhen Peacock Plan (KQTD20180411143628272), and the U.S. National Science Foundation (Award IOS-2019516 to G.J.). W.L. and S.Z. were supported by the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences.

Funding

This work was supported by the Youth Program of National Natural Science Foundation of China (award 32000229 to S.Z.), Shenzhen Peacock Plan (KQTD20180411143628272), and the U.S. National Science Foundation (award IOS-2019516 to G.J.). W.L. and S.Z. were supported by the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences.

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Authors and Affiliations

  1. Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 440307, China

    Renyu Deng, Wei Li & Shaoqun Zhou

  2. Functional Foods Research Unit, Agricultural Research Service, USDA, National Center for Agricultural Utilization Research, 1815 N, University Street, Peoria, IL, 61604, USA

    Mark A. Berhow

  3. Boyce Thompson Institute, Ithaca, NY, 14853, USA

    Georg Jander

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  1. Renyu Deng
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  2. Wei Li
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  4. Georg Jander
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  5. Shaoqun Zhou
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RD and SZ summarized literature and published data, and performed re-analyses. All authors collaboratively drafted the manuscript.

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Correspondence to Shaoqun Zhou.

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Deng, R., Li, W., Berhow, M.A. et al. Phenolic sucrose esters: evolution, regulation, biosynthesis, and biological functions. Plant Mol Biol 109, 369–383 (2022). https://doi.org/10.1007/s11103-021-01142-y

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