Skip to main content

Advertisement

SpringerLink
Log in

Effect of total ecdysteroid preparation from Silene viridiflora on the immune state of experimental animals under normal and secondary immunodeficiency conditions

  • Published:
Pharmaceutical Chemistry Journal Aims and scope

The isolation of total ecdysteroids from Silene viridiflora is described. The preparation acts as an effective immunomodulator in normal animals (mice, 18 – 20 g) and in mice with secondary immunodeficiency developed under irradiation, acute toxic hepatitis, and prolonged physical load conditions. The immunomodulating activity of total ecdysteroids from S. viridiflora is comparable with that of the known immunity stimulator T-activin, a preparation of polypeptide nature from cattle thymus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. W. S. Greuter, Taxon, 44, 543–581 (1995).

    Article  Google Scholar 

  2. O. N. Bondarenko, Guide to Plants of Central Asia [in Russian], Fan, Tashkent (1971), pp. 2, 253.

  3. V. N. Syrov, Eksp. Klin. Farmakol., 57(5), 61–66 (1994).

    PubMed  CAS  Google Scholar 

  4. V. N. Syrov, Zh. I. Islamova, Z. A. Khushbaktova, et al., Vestn. Tinbo (Tashkent), No. 2, 77–83 (2010).

  5. N. Z. Mamadalieva, L. N. Zibareva, Z. Saatov, and R. Lafont, Khim. Prir. Soedin., No. 2, 150–153 (2003).

  6. N. Z. Mamadalieva, L. N. Zibareva, N. Edvard-Todeschi, et al., Coll. Czech. Chem. Commun., 69(8), 1675–1680 (2004).

    Article  CAS  Google Scholar 

  7. N. Z. Mamadalieva, A. A. Janibekov, R. Lafont, and J. P. Girault, Nat. Prod. Commun., 5(10), 1579–1582 (2010).

    PubMed  CAS  Google Scholar 

  8. N. K. Jerne and A. A. Nordin, Science, 140, 405–407 (1963).

    Article  Google Scholar 

  9. M. D. Mashkovskii, Drugs [in Russian], RIA Novaya Volna, Moscow (2008), pp. 736–737.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nizami Tashkent State Pedagogical University, Tashkent, Uzbekistan

    G. A. Shakhmurova

  2. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    N. Z. Mamadalieva, A. A. Zhanibekov, Z. A. Khushbaktova & V. N. Syrov

Authors
  1. G. A. Shakhmurova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. Z. Mamadalieva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. A. Zhanibekov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Z. A. Khushbaktova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. N. Syrov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 46, No. 4, pp. 26 – 28, April, 2012.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shakhmurova, G.A., Mamadalieva, N.Z., Zhanibekov, A.A. et al. Effect of total ecdysteroid preparation from Silene viridiflora on the immune state of experimental animals under normal and secondary immunodeficiency conditions. Pharm Chem J 46, 222–224 (2012). https://doi.org/10.1007/s11094-012-0766-4

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-012-0766-4

Key words

Search

Navigation