The existing assortment of suppository bases has been analyzed with respect to their physicochemical properties. The available data are systematized in the form of a table that provides the classification and summarizes information on the composition, physicochemical properties, and manufacturers. The advantages and disadvantages of suppository bases and possibilities of their usage in ex tempore formulations depending on the production technology and types (vaginal, rectal) are considered.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 44, No. 10, pp. 21 – 26, October, 2010.
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Yarnykh, T.G., Tolochko, E.V. & Chushenko, V.N. Drug synthesis methods and manufacturing technology. Pharm Chem J 44, 551–556 (2011). https://doi.org/10.1007/s11094-011-0516-z
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DOI: https://doi.org/10.1007/s11094-011-0516-z