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Drug synthesis methods and manufacturing technology

Studying an assortment of suppository bases (Review)

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Pharmaceutical Chemistry Journal Aims and scope

The existing assortment of suppository bases has been analyzed with respect to their physicochemical properties. The available data are systematized in the form of a table that provides the classification and summarizes information on the composition, physicochemical properties, and manufacturers. The advantages and disadvantages of suppository bases and possibilities of their usage in ex tempore formulations depending on the production technology and types (vaginal, rectal) are considered.

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References

  1. L. G. Marchenko, A. V. Rusak, and M. E. Smekhova, Farm. Tekhnol. Upakovka, No. 2, 49-60 (2008).

  2. A. I. Tikhonov and T. G. Yarnykh, Drug Technology [in Russian], Original, Kharkov (2006), pp. 407–414.

  3. USP Pharmacists’Pharmacopeia, The United States Pharmacopeia, Inc., Rockville (2008).

  4. Ukraine State Pharmacopeia, Suppl. 2, Derzhavne Pidpriemstvo “Naukovo-Ekspertnii Farmakopeinii Tsentr, Kharkiv (2008).

  5. Kh. M. Komilov, Ya. K. Nazirova, and K. S. Makhmudzhanova, Khim.-farm. Zh., 43(10), 50-51 (2009).

    Google Scholar 

  6. Ukraine Pharmacopeia, Derzhavne Pidpriemstvo “Naukovo-Ekspertnii Farmakopeinii Tsentr, RIREG, Kharkiv (2001).

  7. European Pharmacopoeia, 4th Ed., Strasbourg, Council of Europe (2002).

  8. Ukr. Pat. No. 30,607 (2000); MKI6 A 61 K 9/02.

  9. Ukraine State Pharmacopeia, Suppl. 1, Derzhavne Pidpriemstvo “Naukovo-Ekspertnii Farmakopeinii Tsentr, Kharkiv (2004).

  10. V. A. Golovkin, A. A. Lyul?ko, and A. V. Golovkin, Zaporozhskii Med. Zh., 15(5), 68-71 (2002).

    Google Scholar 

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Correspondence to T. G. Yarnykh.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 44, No. 10, pp. 21 – 26, October, 2010.

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Yarnykh, T.G., Tolochko, E.V. & Chushenko, V.N. Drug synthesis methods and manufacturing technology. Pharm Chem J 44, 551–556 (2011). https://doi.org/10.1007/s11094-011-0516-z

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  • DOI: https://doi.org/10.1007/s11094-011-0516-z

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