Skip to main content

Advertisement

SpringerLink
Log in

Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide

  • Letter to the Editor
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Onda K, Tanaka R, Takahashi H, Takeda N, Ikuta F (1989) Cerebral glioblastoma with cerebrospinal fluid dissemination: a clinicopathological study of 14 cases examined by complete autopsy. Neurosurgery 25:533–540

    Article  PubMed  CAS  Google Scholar 

  2. Ostermann S, Csajka C, Buclin T, Leyvraz S, Lejeune F, Decosterd LA, Stupp R (2004) Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin Cancer Res 10(11):3728–3736

    Article  PubMed  CAS  Google Scholar 

  3. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352(10):987–996

    Article  PubMed  CAS  Google Scholar 

  4. Perry JR, Belanger K, Mason WP, Fulton D, Kavan P, Easaw J et al (2010) Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study. J Clin Oncol 28(12):2051–2057

    Article  PubMed  CAS  Google Scholar 

  5. Roldán G, Scott J, George D, Parney I, Easaw J, Cairncross G, Forsyth P et al (2008) Leptomeningeal disease from oligodendroglioma: clinical and molecular analysis. Can J Neurol Sci 35(2):204–209

    PubMed  Google Scholar 

Download references

Acknowledgments

Both authors have no financial competing interests. Sirisha Nandipati reviewed clinical records and performed a literature review relevant to the case report. She has no financial relationships to disclose. Alexis Demopoulos revised the manuscript for content and was directly involved in the clinical care of both patients. He received financial compensation for: scientific advisory board service for Schering Plough (2008) and Sigma Tau Pharmaceuticals (2008, 2009, and 2010); speaking engagements for Genentech (2009); and royalties from Uptodate.com.

Disclosure

No relevant conflicts of interest to disclose.

Author information

Authors and Affiliations

  1. Mount Sinai School of Medicine, 50 E 98th Street, #14G, New York, NY, 10029, USA

    Sirisha Nandipati

  2. Tisch Cancer Institute and Departments of Neurosurgery and Neurology, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1079, New York, NY, 10029, USA

    Alexis Demopoulos

Authors
  1. Sirisha Nandipati
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Alexis Demopoulos
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alexis Demopoulos.

Additional information

Sirisha Nandipati contributed equally to the manuscript.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nandipati, S., Demopoulos, A. Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide. J Neurooncol 105, 663–665 (2011). https://doi.org/10.1007/s11060-011-0611-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11060-011-0611-8

Keywords

Search

Navigation