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Web-based Multi-center Data Management System for Clinical Neuroscience Research

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Abstract

Modern clinical research often involves multi-center studies, large and heterogeneous data flux, and intensive demands of collaboration, security and quality assurance. In the absence of commercial or academic management systems, we designed an open-source system to meet these requirements. Based on the Apache-PHP-MySQL platform on a Linux server, the system allows multiple users to access the database from any location on the internet using a web browser, and requires no specialized computer skills. Multi-level security system is implemented to safeguard the protected health information and allow partial or full access to the data by individual or class privilege. The system stores and manipulates various types of data including images, scanned documents, laboratory data and clinical ratings. Built-in functionality allows for various search, quality control, analytic data operations, visit scheduling and visit reminders. This approach offers a solution to a growing need for management of large multi-center clinical studies.

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Acknowledgements

This work was supported by NIH grant # NS043488. We thank Janet Ben-Mordechai, RN, Ilana Seror, B.Sc., and Vered Luufman-Malkin, CSW, for their assistance with the development and utilization of the system.

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Authors and Affiliations

  1. Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA

    Alexander Pozamantir, Hedok Lee & Isak Prohovnik

  2. Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA

    Isak Prohovnik

  3. Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel

    Joab Chapman

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  1. Alexander Pozamantir
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  2. Hedok Lee
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  4. Isak Prohovnik
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Correspondence to Isak Prohovnik.

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Pozamantir, A., Lee, H., Chapman, J. et al. Web-based Multi-center Data Management System for Clinical Neuroscience Research. J Med Syst 34, 25–33 (2010). https://doi.org/10.1007/s10916-008-9212-2

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  • DOI: https://doi.org/10.1007/s10916-008-9212-2

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