Skip to main content
SpringerLink
Log in

Rapid Green Synthesis of Silver Nanoparticles Using Ethiopian Cactus Pear Fruit Peel Infusions and Evaluation of Its In Vitro Clinical Potentials

  • Communication
  • Published:
Journal of Inorganic and Organometallic Polymers and Materials Aims and scope Submit manuscript

Abstract

In the current study, the Ethiopian cactus pear fruit peel infusions were used as a phytoreducing agent to fabricate silver nanoparticles (CPFP-AgNPS). The formation of AgNPS in 7 min was confirmed by Ultra UV–Vis spectral portrait. The average size range (20–60 nm), the composition of silver element and crystal structure of the CPFP-AgNPS was established by transmission electron microscopy, energy dispersive X-ray spectra and X-ray diffraction analysis respectively. The CPFP-AgNPS exhibited greater inhibition (81.92%) on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay. The antibacterial activity of CPFP-AgNPS was high in the order against E.coli > Salmonella spp. > Bacillus spp. > Pseudomonas spp. > Staphylococcus spp. respectively. The CPFP-AgNPS also showed effective anticancer activity against human cervix epithelioid carcinoma cell lines with an IC50 value of 74.26 ± 0.25 µg mL−1/24 h. In short, the findings highlighted the effectiveness of CPFP-AgNPS on potential therapeutic applications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

References

  1. F. Ameen, P. Srinivasan, T. Selvankumar, S. Kamala-Kannan, S. Al Nadhari, A. Almansob, T. Dawoud, M. Govarthanan, Bioorg. Chem. 88, 1 (2019)

    Article  Google Scholar 

  2. T.H. Reda, M.K. Atsbha, Int. J. Food Sci. 2019, 1 (2019)

    Article  Google Scholar 

  3. X. Lai, R. Guo, H. Xiao, J. Lan, S. Jiang, C. Cui, E. Ren, J. Hazard. Mater. 371, 506 (2019)

    Article  CAS  Google Scholar 

  4. W. Brand-Williams, M.E. Cuvelier, C. Berset, LWT-Food Sci. Technol. 28, 25 (1995)

    Article  CAS  Google Scholar 

  5. N.J. Reddy, D. Nagoor Vali, M. Rani, S.S. Rani, Mater. Sci. Eng. C 34, 115 (2014)

    Article  CAS  Google Scholar 

  6. A.A. van de Loosdrecht, R.H.J. Beelen, G.J. Ossenkoppele, M.G. Broekhoven, M.M.A.C. Langenhuijsen, J. Immunol. Methods 174, 311 (1994)

    Article  Google Scholar 

  7. S. Francis, S. Joseph, E.P. Koshy, B. Mathew, Artif. Cells Nanomed Biotechnol. 46, 795 (2018)

    Article  CAS  Google Scholar 

  8. S. Pal, Y.K. Tak, J.M. Song, Appl. Environ. Microbiol. 73, 1712 (2007)

    Article  CAS  Google Scholar 

  9. M. Vanaja, K. Paulkumar, M. Baburaja, S. Rajeshkumar, G. Gnanajobitha, C. Malarkodi, M. Sivakavinesan, G. Annadurai, Bioinorg. Chem. Appl. 2014, 1 (2014)

    Article  Google Scholar 

  10. B. Senthil, T. Devasena, B. Prakash, A. Rajasekar, J. Photochem. Photobiol. B 177, 1 (2017)

    Article  CAS  Google Scholar 

  11. M. Rai, A. Yadav, A. Gade, Biotechnol. Adv. 27, 76 (2009)

    Article  CAS  Google Scholar 

  12. F. Sambale, S. Wagner, F. Stahl, R.R. Khaydarov, T. Scheper, D. Bahnemann, J. Nanomater. 2015, 1 (2015)

    Google Scholar 

  13. M.A. Rahman, A. Hussain, Bangl. J. Pharmacol. 10, 27 (2015)

    Google Scholar 

  14. R.M. Patel, S.K. Patel, J. Appl. Pharm. Sci. 1, 167 (2011)

    Google Scholar 

  15. Z.A. Ratan, M.F. Haidere, M. Nurunnabi, S.M. Shahriar, A.J.S. Ahammad, Y.Y. Shim, M.J.T. Reaney, J.Y. Cho, Cancers (Basel). 12, 1 (2020)

    Article  Google Scholar 

Download references

Acknowledgements

The authors are thankful to Addis Ababa Science and Technology University, Ethiopia for providing lab facilities for this work and SRM Institute of Science and Technology, India for providing extended support for the nanomaterial characterization studies. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Author information

Authors and Affiliations

  1. Department of Biotechnology, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, 16417, Addis Ababa, Ethiopia

    M. Kamaraj & Kidist Mulugeta

  2. Nanotechnology Center of Excellence, Addis Ababa Science and Technology University, 16417, Addis Ababa, Ethiopia

    M. Kamaraj

  3. Department of Biotechnology, FSH, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India

    T. G. Nithya & P. Santhosh

Authors
  1. M. Kamaraj
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. G. Nithya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Santhosh
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kidist Mulugeta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. Kamaraj.

Ethics declarations

Conflict of interest

The authors did not declare any conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kamaraj, M., Nithya, T.G., Santhosh, P. et al. Rapid Green Synthesis of Silver Nanoparticles Using Ethiopian Cactus Pear Fruit Peel Infusions and Evaluation of Its In Vitro Clinical Potentials. J Inorg Organomet Polym 30, 3832–3836 (2020). https://doi.org/10.1007/s10904-020-01549-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10904-020-01549-y

Keywords

Search

Navigation