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Prevalence of Tuberculosis and Mental Disorders Comorbidity: A Systematic Review and Meta-analysis

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Abstract

Persons with tuberculosis (TB) also often have a mental disorder (MD). We examined TB-MD comorbidity prevalence and its impact on TB treatment outcomes as reported in studies set in the United States or in the top five countries of origin (Mexico, the Philippines, India, Vietnam, and China) for non-US–born persons with TB. We searched MEDLINE, EMBASE, OVID, PsycINFO, CINAHL, and Scopus for articles published from database inception through September 2018. Of the 9 studies analyzed, one was set in the United States. The estimated pooled prevalence of comorbid TB-MD from eight non-US studies, with 2921 participants, was 34.0% [95% confidence interval (CI) 21.1%–49.5%]. Comorbid TB-MD prevalence varied by country in the studies evaluated. Additional research might elucidate the extent of TB-MD in the United States and the top five countries of origin.

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Acknowledgements

The authors thank Joanna Taliano from the Stephen B. Thacker CDC Library for her assistance in conducting the literature search. The authors are also grateful to Roque Miramontes, Maureen Kolasa, Andrew Hill, and C. Kay Smith for the support provided throughout the review and manuscript development process.

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  1. Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop US12-4, Atlanta, GA, 30329-4027, USA

    Gibril J. Njie & Awal Khan

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Njie, G.J., Khan, A. Prevalence of Tuberculosis and Mental Disorders Comorbidity: A Systematic Review and Meta-analysis. J Immigrant Minority Health 24, 1550–1556 (2022). https://doi.org/10.1007/s10903-021-01312-6

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