Abstract
Mosquito control is facing a challenge worldwide, due to ineffectiveness of chemical insecticides. Identification of novel and ecofriendly insecticides is the need of the hour. In the present study mosquito control efficacy, antioxidants and anti-cancerous potential of silver nanoparticle conjugated with Carmona retusa (Vahl) Masam nanoparticles. Synthesized nanoparticles had UV absorption maximum at 420 nm, size ranging between 20 and 40 nm based of TEM, has cubic structure, C–H bending and Ag Metal bands. Results show high free radical scavenging ability of C. retusa derived silver nanoparticles as evidenced by DPPH radical and H2O2 radical assay. C. retusa derived nanoparticles produce 80% inhibition in MCF-7 cell line at concentration of 500 μg/ml. High larvicidal activity with LC50 values of 116.681 ppm for Anopheles stephensi, 198.766 ppm for Aedes aegypti, and 83.553 ppm for Culex quinquefasciatus were observed. Based on the findings of the study we suggest that C. retusa plant mediated AgNPs has anticancerous and mosquito larvicidal property and could be bioprospected for drug development and mosquito control.
Similar content being viewed by others
References
S. Kaviya, J. Santhanalakshmi, and B. Viswanathan (2011). J. Nanotechnol. 5, 1.
S. S. Shankar, A. Rai, A. Ahmad, and M. Sastry (2004). J. Colloid Interface Sci. 275, 496.
J. Huang, Q. Li, D. Sun, Y. Lu, Y. Su, X. Yang, H. Wang, Y. Wang, W. Shao, N. He, J. Hong, and C. Chen (2007). Nanotechnology 18, 105104.
C.-N. Lok, C.-M. Ho, R. Chen, Q.-Y. He, W.-Y. Yu, H. Sun, P. K. Tam, J.-F. Chiu, and C.-M. Che (2007). J. Biol. Inorg. Chem. 12, 527.
M. A. Albrecht, C. W. Evan, and C. L. Raston (2006). Green Chem. 8, 417.
P. Vivekanandhan, S. Deepa, E. J. Kweka, and M. S. Shivakumar (2018). J. Clust. Sci. https://doi.org/10.1007/s10876-018-1423-1.
S. Coe, W.-K. Woo, M. Bawendi, and V. Bulovic (2002). Nature 420, 800.
V. K. Sharma, R. A. Yngard, and Y. Lin (2009). Adv. Colloid Interface Sci. 145, 83.
G. Benelli and C. M. Lukehart (2017). J. Clust. Sci. 28, 1.
M. Gorbe, R. Bhat, E. Aznar, F. Sancenon, M. D. Marcos, F. J. Herraiz, J. Prohens, A. Venkataraman, and R. Martinez-Manez (2016). Materials 9, 325.
L. S. De Padua, G. C. Lugod, and J. V. Pancho (1980). UPLB Philippines 1, 21.
WHO (2016). Zika virus. Fact sheet N°1. Updated January 2016.
G. Benelli and J. Beier (2017). Acta Trop. 174, 91.
G. Benelli and D. Romano (2017). Entomol. Gen. 36, 309. https://doi.org/10.1127/entomologia/2017/0496.
World Health Organization. (2017). Geniva. www.Who.int/mediacentre/factsheets/fs387/en/2017. Accessed on 22/02/2018.
G. Benelli and M. F. Duggan (2018). Acta. Trop. 182, 80.
WHO. (1999). Geneva: World Health Organization. http://www.who.int/inf-fs/en/fact094.html.
G. Benelli and H. Mehlhorn (2016). Parasitol. Res. 115, 1747.
L. Bernhard, P. Bernhard, and P. Magnussen (2003). Physiotherapy. 89, 743.
World Health Organization. (2002). Geneva. www.who.int/whr/2002/en/.
World Health Organization. (2016). Geneva. www.who.int/whopes/en/2016. edn 2.
I. Mahmood, S. R. Imadi, K. Shazadi, A. Gul, K. R. Hakeem, K. Hakeem, M. Akhtar, and S. Abdullah (2016). Cham 1, 253.
N. Macagnan, C. F. Rutkoski, C. Kolcenti, G. V. Vanzetto, L. P. Macagnan, P. F. Sturza, P. A. Hartmann, and M. T. Hartmann (2017). Environ. Sci. Pollut. Res. 24, 20699.
G. Benelli (2015). Parasitol. Res. 114, 2801.
P. Vivekanandhan, R. Venkatesan, G. Ramkumar, S. Karthi, S. Senthil-Nathan, and M. S. Shivakumar (2018). Int. J. Environ. Res. Pub. Health 15, 388. https://doi.org/10.3390/ijerph15020388.
G. Benelli (2016). Enzyme Microb. Technol. 95, 58.
P. Sowndarya, G. Ramkumar, and M. S. Shivakumar (2017). Artif. Cells Nanomed. Biotechnol. 45, 1490.
M. Rai, A. Yadav, and A. Gade (2009). Biotechnol. Adv. 27, 76.
P. Molyneux (2004). J. Sci. Technol. 26, 211.
B. Halliwell, J. M. Gutteridge, and O. I. Aruoma (1987). Anal. Biochem. 165, 215.
T. Mosmann (1983). J. Immunol. Methods 65, 55.
World Health Organization. (2005). Geneva. www.WHO/CDS/WHOPES/GCDPP/13.
W. S. Abbott (1925). J. Ecol. Entomol. 18, 265.
B. Kumar, K. Smita, L. Cumbal, and Y. Angulo (2015). J. Mol. Liq. 211, 476.
R. Vivek, R. Thangam, K. Muthuchelian, P. Gunasekaran, and K. S. Kaveri Kannan (2012). Process Biochem. 47, 2405.
S. Francis, S. Joseph, E. P. Koshy, and B. Mathew (2017). Environ. Sci. Pollut. Res. 24, 17347.
N. J. Reddy, D. N. Vali, M. Rani, and S. S. Rani (2014). Mater. Sci. Eng. C 34, 115.
P. C. Nagajyothi, S. J. Cha, I. J. Yang, T. V. Sreekanth, K. J. Kim, and H. M. Shin (2015). J. Photochem. Photobiol. B 146, 10.
R. L. Baldwin (1968). A Rev. J. Dairy Sci. 51, 104.
C. S. Ryu, C. H. Kim, S. Y. Lee, K. S. Lee, K. J. Choung, G. Y. Song, B. H. Kim, S. Y. Ryu, H. S. Lee, and S. K. Kim (2012). Food Chem. 132, 333.
G. Kiran, M. Sarangapani, T. Gouthami, and A. R. Narsimha Reddy (2013). Toxicol. Environ. Chem. 95, 367.
G. C. Yen and H. Y. Chen (1995). J. Agric. Food Chem. 43, 27.
K. Gopinath, M. Chinnadurai, N. P. Devi, K. Bhakyaraj, S. Kumaraguru, T. Baranisri, A. Sudha, M. Zeeshan, A. Arumugam, M. Govindarajan, N. S. Alharbi, S. Kadaikunnan, and G. Benelli (2017). J. Clust. Sci. 28, 621.
G. Benelli (2018). Environ. Sci. Pollut. Res. Int. 25, 12329–12341. https://doi.org/10.1007/s11356-018-1850-4.
G. Benelli (2018). Acta Trop. 178, 73. https://doi.org/10.1016/j.actatropica.2017.10.021.
C. G. Athanassiou, N. G. Kavallieraros, G. Benelli, D. Losic, P. Usha Rani, and N. Desneux (2018). J. Pest Sci. 91, 1.
Acknowledgements
This research was funded by University Grants Commission-Rajiv Gandhi National Fellowship Programme (Sanction Number: F1-17.1/2016-17/RGNF-2015-17-SC-TAM-26510) for their financial support. The authors thank Department of Botany, School of life Sciences, Periyar University, Salem, Tamil Nadu, India, for infrastructural support and KIRND Institute of Research and Development Pvt Ltd, Tiruchirappalli, Tamil Nadu, India.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Rights and permissions
About this article
Cite this article
Rajkumar, R., Shivakumar, M.S., Senthil Nathan, S. et al. Pharmacological and Larvicidal Potential of Green Synthesized Silver Nanoparticles Using Carmona retusa (Vahl) Masam Leaf Extract. J Clust Sci 29, 1243–1253 (2018). https://doi.org/10.1007/s10876-018-1443-x
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10876-018-1443-x