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TiO2 nanotubes modified with polydopamine and graphene quantum dots as a photochemical biosensor for the ultrasensitive detection of glucose

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Abstract

Rapid and sensitive detection of glucose concentrations is very important for human health. Herein, an ultrasensitive photoelectrochemical dual-electron-acceptor biosensor was constructed by modifying the TiO2 nanotubes (NTs) with polydopamine (PDA) and amino-functionalized graphene quantum dots (N-GQDs)/GOx. PDA is grown on the top of the TiO2 NTs by the electropolymerization, and N-GQDs are loaded into the inner of the TiO2 NTs by a microwave-assisted method. The TiO2 NTs/PDA/N-GQD dual-electron-acceptor biosensor exhibited a highly enhanced photoelectric response, excellent electron–hole separation efficiency, low detection limit (0.015 mM), wide linear range (0–11 mM) and ultrahigh sensitivity (13.6 µA mM−1 cm−2). The prepared biosensor reflected high selectivity and excellent stability. This work also provides new insights into other optoelectronic biosensors.

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Acknowledgements

This research was financially supported by Key Research and Development Project of Hainan Province (No. ZDYF2018106), National Natural Science Foundation of China (Nos. 51762012, and 51862006) and Key Laboratory Open Project Fund of Hainan University (2018008).

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Authors and Affiliations

  1. State Key Laboratory of Marine Resource Utilization in South China Sea, College of Materials and Chemical Engineering, Hainan University, Haikou, 570228, People’s Republic of China

    Wenke Yang, Wei Xu, Nan Zhang, Yang Cao & Jinchun Tu

  2. Laboratory Cultivation Base of Natural Gas Conversion, School of Chemistry and Chemical Engineering, Ningxia University, Yinchuan, 750021, People’s Republic of China

    Xiaoyong Lai & Juan Peng

  3. Qiongtai Normal University, Haikou, 571127, Hainan, People’s Republic of China

    Yang Cao

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  1. Wenke Yang
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  2. Wei Xu
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Correspondence to Jinchun Tu.

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Yang, W., Xu, W., Zhang, N. et al. TiO2 nanotubes modified with polydopamine and graphene quantum dots as a photochemical biosensor for the ultrasensitive detection of glucose. J Mater Sci 55, 6105–6117 (2020). https://doi.org/10.1007/s10853-020-04422-y

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