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Laryngeal mask airway versus endotracheal intubation as general anesthesia airway managements for atrial fibrillation catheter ablation: a comparative analysis based on propensity score matching

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Abstract

Background

The current evidence on the use of laryngeal mask airway (LMA) as an airway management technique for general anesthesia (GA) during atrial fibrillation (AF) catheter ablation (CA) is insufficient. This study aims to compare the feasibility, safety, and clinical benefits of LMA and endotracheal intubation (ETI) for airway management in AF CA.

Methods

One hundred fifty-two consecutive patients with AF who underwent CA under GA were included and divided into two groups based on different airway management methods (66 in the LMA group, 86 in the ETI group). After propensity score matching, a final analysis cohort of 132 patients was obtained to compare procedural parameters, adverse events, and prognosis between the two groups.

Results

The LMA group exhibited significantly shorter total procedural time (p = 0.039), anesthesia induction time (p = 0.015), and recovery time (p = 0.006) compared to the ETI group. The mean arterial pressure (MAP) and heart rate were significantly lower in the LMA group during extubation and 1-min post-extubation (p < 0.05). Furthermore, the LMA group demonstrated lower MAP levels during intubation (p = 0.029). The incidences of intraoperative hypotension (p = 0.017) and bradycardia (p = 0.032) were significantly lower in the LMA group. The incidences of delayed recovery or delirium (p = 0.027), laryngeal or airway injury (p = 0.016), cough or bucking (p = 0.001), and sore throat (p < 0.001) were significantly lower in the LMA group. There were no statistically significant differences in catheter stability parameters and sinus rhythm maintenance rates between the two groups (p > 0.05).

Conclusion

LMA is feasible, safe, and effective in AF CA as an optimized airway management technique for GA.

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Abbreviations

ACT:

Activated coagulation time

AF:

Atrial fibrillation

AI:

Ablation index

CA:

Catheter ablation

CF:

Contact force

ECG:

Electrocardiogram

ETI:

Endotracheal intubation

GA:

General anesthesia

HR:

Heart rate

LMA:

Laryngeal mask airway

MAP:

Mean arterial pressure

NOAC:

Novel oral anticoagulant

PAF:

Paroxysmal atrial fibrillation

PsAF:

Persistent atrial fibrillation

PSM:

Propensity score matching

PVI:

Pulmonary vein isolation

RF:

Radiofrequency

References

  1. Silva RMFLD, Miranda CM, Liu T, et al. Atrial fibrillation and risk of dementia: epidemiology, mechanisms, and effect of anticoagulation. Front Neurosci. 2019;31(13):18.

    Article  Google Scholar 

  2. Virani SS, Alonso A, Benjamin EJ, et al. Heart disease and stroke statistics-2020 update: a report from the American Heart Association. Circulation. 2020;141(9):e139.

    Article  PubMed  Google Scholar 

  3. Du X, Guo L, Xia S, et al. Atrial fibrillation prevalence, awareness and management in a nationwide survey of adults in China. Heart. 2021;107(7):535–41.

    Article  PubMed  Google Scholar 

  4. Andersson T, Magnuson A, Bryngelsson IL, et al. All-cause mortality in 272,186 patients hospitalized with incident atrial fibrillation 1995-2008: a Swedish nationwide long-term case-control study. Eur Heart J. 2013;34(14):1061–7.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Kirchhof P, Camm AJ, Goette A, et al. Early rhythm-control therapy in patients with atrial fibrillation. N Engl J Med. 2020;383(14):1305–16.

    Article  PubMed  Google Scholar 

  6. January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons. Circulation. 2019;140(2):e125–51.

    Article  PubMed  Google Scholar 

  7. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(5):373–498.

    Article  PubMed  Google Scholar 

  8. Chikata A, Kato T, Yaegashi T, et al. General anesthesia improves contact force and reduces gap formation in pulmonary vein isolation: a comparison with conscious sedation. Heart Vessels. 2017;32(8):997–1005.

    Article  PubMed  Google Scholar 

  9. Garcia R, Waldmann V, Vanduynhoven P, et al. Worldwide sedation strategies for atrial fibrillation ablation: current status and evolution over the last decade. Europace. 2021;23(12):2039–45.

    Article  PubMed  Google Scholar 

  10. Pang N, Gao J, Zhang N, et al. Comparison of the different anesthesia strategies for atrial fibrillation catheter ablation: a systematic review and meta-analysis. Cardiol Res Pract. 2022;2022:1124372.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Dada RS, Hayanga JWA, Woods K, et al. Anesthetic choice for atrial fibrillation ablation: a National Anesthesia Clinical Outcomes Registry analysis. J Cardiothorac Vasc Anesth. 2021;35(9):2600–6.

    Article  PubMed  Google Scholar 

  12. Vaida S, Gaitini L, Somri M, et al. Airway management during the last 100 years. Crit Care Clin. 2023;39(3):451–64.

    Article  PubMed  Google Scholar 

  13. Bhushan D, Nandkumar S, Butani M. The comparison between supreme laryngeal mask airway and endotracheal tube with respect to adequacy of ventilation in patients undergoing laparoscopic cholecystectomy under general anesthesia-a prospective, randomized, double-blind study, and comparative study. Asian J Anesthesiol. 2022;60

  14. Webb N, Kars MS, Butler AL, et al. The use of laryngeal mask airway for tonsillectomy and adenoidectomy. Int J Pediatr Otorhinolaryngol. 2021;144:110691.

    Article  PubMed  Google Scholar 

  15. Park S, Lee JE, Choi GS, et al. Second-generation laryngeal mask airway as an alternative to endotracheal tube during prolonged laparoscopic abdominal surgery: a comparative analysis of intraoperative gas exchanges. Singapore Med J. 2021;64(11):651–6.

    Article  PubMed Central  Google Scholar 

  16. Kang SH, Park M. Comparison of early postoperative recovery between laryngeal mask airway and endotracheal tube in laparoscopic cholecystectomy: a randomized trial. Medicine (Baltimore). 2019;98(25):e16022.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Benedetto U, Head SJ, Angelini GD, et al. Statistical primer: propensity score matching and its alternatives. Eur J Cardiothorac Surg. 2018;53(6):1112–7.

    Article  PubMed  Google Scholar 

  18. Rosenbaum PR, Rubin DB. The central role of the propensity score in observational studies for causal effect. Biometrika. 1983;70(1):41–55.

    Article  Google Scholar 

  19. Kirchhof P, Auricchio A, Bax J, et al. Outcome parameters for trials in atrial fibrillation: recommendations from a consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. Europace. 2007;9(11):1006–23.

    Article  PubMed  Google Scholar 

  20. Calkins H, Hindricks G, Cappato R, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2017;14(10):e275–444.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Eitel C, Piorkowski C, Hindricks G. Clinical relevance and management of early recurrences after catheter ablation of atrial fibrillation. Expert Rev Cardiovasc Ther. 2011;9(7):849–52.

    Article  PubMed  Google Scholar 

  22. Silva MR, Silva GS, Fernandes S, et al. Clinical relevance of the blanking period on late recurrence after catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2023;34(1):24–34.

    Article  PubMed  Google Scholar 

  23. Homberg MC, Bouman EAC, Joosten BAJ. Optimization of procedural sedation and analgesia during atrial fibrillation ablation. Curr Opin Anaesthesiol. 2023;36(3):354–60.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Osorio J, Rajendra A, Varley A, et al. General anesthesia during atrial fibrillation ablation: standardized protocol and experience. Pacing Clin Electrophysiol. 2020;43(6):602–8.

    Article  PubMed  Google Scholar 

  25. Tang RB, Dong JZ, Zhao WD, et al. Unconscious sedation/analgesia with propofol versus conscious sedation with fentanyl/midazolam for catheter ablation of atrial fibrillation: a prospective, randomized study. Chin Med J (Engl). 2007;120(22):2036–8.

    Article  PubMed  CAS  Google Scholar 

  26. Kottkamp H, Hindricks G, Eitel C, et al. Deep sedation for catheter ablation of atrial fibrillation: a prospective study in 650 consecutive patients. J Cardiovasc Electrophysiol. 2011;22(12):1339–43.

    Article  PubMed  Google Scholar 

  27. Salukhe TV, Willems S, Drewitz I, et al. Propofol sedation administered by cardiologists without assisted ventilation for long cardiac interventions: an assessment of 1000 consecutive patients undergoing atrial fibrillation ablation. Europace. 2012;14(3):325–30.

    Article  PubMed  Google Scholar 

  28. Wutzler A, Loehr L, Huemer M, et al. Deep sedation during catheter ablation for atrial fibrillation in elderly patients. J Interv Card Electrophysiol. 2013;38(2):115–21.

    Article  PubMed  Google Scholar 

  29. Di Biase L, Conti S, Mohanty P, et al. General anesthesia reduces the prevalence of pulmonary vein reconnection during repeat ablation when compared with conscious sedation: results from a randomized study. Heart Rhythm. 2011;8(3):368–72.

    Article  PubMed  Google Scholar 

  30. Calkins H, Kuck KH, Cappato R, et al. 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol. 2012;33(2):171–257.

    Article  PubMed  Google Scholar 

  31. Gerstein NS, Young A, Schulman PM, et al. Sedation in the electrophysiology laboratory: a multidisciplinary review. J Am Heart Assoc. 2016;5(6):e003629.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Apfelbaum JL, Hagberg CA, Connis RT, et al. 2022 American Society of Anesthesiologists Practice Guidelines for management of the difficult airway. Anesthesiology. 2022;136(1):31–81.

    Article  PubMed  Google Scholar 

  33. Tikka T, Hilmi OJ. Upper airway tract complications of endotracheal intubation. Br J Hosp Med (Lond). 2019;80(8):441–7.

    Article  PubMed  Google Scholar 

  34. Koyama T, Kobayashi M, Ichikawa T, et al. Laryngeal mask versus facemask in the respiratory management during catheter ablation. BMC Anesthesiol. 2020;20(1):9.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Hernandez MR, Klock PA Jr, Ovassapian A. Evolution of the extraglottic airway: a review of its history, applications, and practical tips for success. Anesth Analg. 2012;114(2):349–68.

    Article  PubMed  Google Scholar 

  36. Van Zundert TC, Brimacombe JR, Ferson DZ, et al. Archie Brain: celebrating 30 years of development in laryngeal mask airways. Anaesthesia. 2012;67(12):1375–85.

    Article  PubMed  Google Scholar 

  37. Wei CF, Chung YT. Laryngeal mask airway facilitates a safe and smooth emergence from anesthesia in patients undergoing craniotomy: a prospective randomized controlled study. BMC Anesthesiol. 2023;23(1):29.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  38. Karaaslan E, Akbas S, Ozkan AS, et al. A comparison of laryngeal mask airway-supreme and endotracheal tube use with respect to airway protection in patients undergoing septoplasty: a randomized, single-blind, controlled clinical trial. BMC Anesthesiol. 2021;21(1):5.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  39. Song Z, Tan J, Fang J, et al. Comparison of laryngeal mask airway and endotracheal intubation in gynecological cancer operation. Oncol Lett. 2019;17(2):2344–50.

    PubMed  Google Scholar 

  40. Yao WY, Li SY, Yuan YJ, et al. Comparison of supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for cesarean section: a randomized controlled trial. BMC Anesthesiol. 2019;19(1):123.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Zaman B, Noorizad S, Safari S, et al. Efficacy of laryngeal mask airway compared to endotracheal tube: a randomized clinical trial. Anesth Pain Med. 2022;12(1):e120478.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Balmforth D, Smith A, Nagore D, et al. Can transesophageal echocardiography be performed safely using a laryngeal mask airway during atrial fibrillation ablation? J Cardiothorac Vasc Anesth. 2018;32(2):790–5.

    Article  PubMed  Google Scholar 

  43. Fox EJ, Sklar GS, Hill CH, et al. Complications related to the pressor response to endotracheal intubation. Anesthesiology. 1977;47(6):524–5.

    Article  PubMed  CAS  Google Scholar 

  44. Onishi N, Kaitani K, Nakagawa Y, et al. The association between late-phase early recurrence within the blanking period after atrial fibrillation catheter ablation and long-term recurrence: insights from a large-scale multicenter study. Int J Cardiol. 2021;341:39–45.

    Article  PubMed  Google Scholar 

  45. Kahl M, Eberhart LH, Behnke H, et al. Stress response to tracheal intubation in patients undergoing coronary artery surgery: direct laryngoscopy versus an intubating laryngeal mask airway. J Cardiothorac Vasc Anesth. 2004;18(3):275–80.

    Article  PubMed  Google Scholar 

  46. Akbar AN, Muzi M, Lopatka CW, et al. Neurocirculatory responses to intubation with either an endotracheal tube or laryngeal mask airway in humans. J Clin Anesth. 1996;8(3):194–7.

    Article  PubMed  CAS  Google Scholar 

  47. Mizrak A, Kocamer B, Deniz H, et al. Cardiovasular changes after placement of a classic endotracheal tube, double-lumen tube, and laryngeal mask airway. J Clin Anesth. 2011;23(8):616–20.

    Article  PubMed  Google Scholar 

  48. Pernerstorfer T, Krafft P, Fitzgerald RD, et al. Stress response to tracheal intubation: direct laryngoscopy compared with blind oral intubation. Anaesthesia. 1995;50(1):17–22.

    Article  PubMed  CAS  Google Scholar 

  49. Barak M, Ziser A, Greenberg A, et al. Hemodynamic and catecholamine response to tracheal intubation: direct laryngoscopy compared with fiberoptic intubation. J Clin Anesth. 2003;15(2):132–6.

    Article  PubMed  Google Scholar 

  50. Song Z, Tan J, Fang J, et al. Comparison of laryngeal mask airway and endotracheal intubation in gynecological cancer operation. Oncol Lett. 2019;17(2):2344–50.

    PubMed  Google Scholar 

  51. Ismail SA, Bisher NA, Kandil HW, et al. Intraocular pressure and haemodynamic responses to insertion of the i-gel, laryngeal mask airway or endotracheal tube. Eur J Anaesthesiol. 2011;28(6):443–8.

    Article  PubMed  Google Scholar 

  52. Wiederstein I, Auer U, Moens Y. Laryngeal mask airway insertion requires less propofol than endotracheal intubation in dogs. Vet Anaesth Analg. 2006;33(4):201–6.

    Article  PubMed  CAS  Google Scholar 

  53. Zhang Q, Sun Y, Wang B, et al. Comparative study of the Ambu® AuraOnce™ laryngeal mask and endotracheal intubation in anesthesia airway management during neurosurgery. J Int Med Res. 2020;48(2):300060520902606.

    Article  PubMed  Google Scholar 

  54. Ashay NA, Wasim S, Anil TB. Propofol requirement for insertion of I-gel versus laryngeal mask airway: a comparative dose finding study using Dixon’s up-and-down method. J Anaesthesiol Clin Pharmacol. 2015;31(3):324–8.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  55. Carron M, Veronese S, Gomiero W, et al. Hemodynamic and hormonal stress responses to endotracheal tube and ProSeal Laryngeal Mask Airway™ for laparoscopic gastric banding. Anesthesiology. 2012;117(2):309–20.

    Article  PubMed  Google Scholar 

  56. An G, Fang B, Wang Z. Comparing the insertion and ventilation of laryngeal mask airway according to the patient’s head position and muscle relaxation use. A prospective clinical trial. Saudi Med J. 2019;40(7):687–93.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Ambrogi MC, Fanucchi O, Korasidis S, et al. Nonintubated thoracoscopic pulmonary nodule resection under spontaneous breathing anesthesia with laryngeal mask. Innovations (Phila). 2014 9 (4): 276-80.

  58. Totonchi Z, Seyed Siamdoust SA, Zaman B, et al. Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial. Heliyon. 2022;8(11):e11504.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  59. Bai P, Huai W, Xia T, et al. Time comparison of artificial airway establishment in operating room and on slope using endotracheal intubation and laryngeal mask. Beijing Da Xue Xue Bao Yi Xue Ban. 2022;54(1):166–9. Chinese

    PubMed  CAS  Google Scholar 

  60. Hashemian AM, Zamani Moghadam Doloo H, Saadatfar M, et al. Effects of intravenous administration of fentanyl and lidocaine on hemodynamic responses following endotracheal intubation. Am J Emerg Med. 2018;36(2):197–201.

    Article  PubMed  Google Scholar 

  61. Reddy VY, Dukkipati SR, Neuzil P, et al. Randomized, controlled trial of the safety and effectiveness of a contact force-sensing irrigated catheter for ablation of paroxysmal atrial fibrillation: results of the TactiCath Contact Force Ablation Catheter Study for Atrial Fibrillation (TOCCASTAR) Study. Circulation. 2015;132(10):907–15.

    Article  PubMed  Google Scholar 

  62. Kautzner J, Neuzil P, Lambert H, et al. EFFICAS II: optimization of catheter contact force improves outcome of pulmonary vein isolation for paroxysmal atrial fibrillation. Europace. 2015;17(8):1229–35.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Xu R, Lian Y, Li WX. Airway complications during and after general anesthesia: a comparison, systematic review and meta-analysis of using flexible laryngeal mask airways and endotracheal tubes. PLoS One. 2016;11(7):e0158137.

    Article  PubMed  PubMed Central  Google Scholar 

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Funding

This study was supported by the National Natural Science Foundation of China (Grant/Award Number: 82000426); the Natural Science Foundation of Shanxi Province, China (Grant/Award Number: 201801D121222 and 201801D121337); and the Cultivation Project of Young and Middle-aged Academic Leaders of the First Hospital of Shanxi Medical University (Grant/Award Number: YD1609).

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Study concept and design: RW and NP. Data acquisition: NP, FP, RC, and BZ. Formal analysis: NP, FP, and ZY. Writing—original draft preparation: NP; writing—review and editing: RW and MG. Funding acquisition: RW and MG.

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Correspondence to Rui Wang.

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Pang, N., Pan, F., Chen, R. et al. Laryngeal mask airway versus endotracheal intubation as general anesthesia airway managements for atrial fibrillation catheter ablation: a comparative analysis based on propensity score matching. J Interv Card Electrophysiol (2024). https://doi.org/10.1007/s10840-024-01742-w

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