Abstract
Uncommon association of left anterior fascicular ventricular tachycardia (VT) with a healed myocardial infarction (MI) is described. A 55-year-old man with a history of anteroseptal MI had verapamil-sensitive VT. The VT exhibited a right bundle branch block configuration and right-axis deviation. The VT exit was located at the left ventricular anterolateral wall. At the mid-anterior left ventricular septum, delayed Purkinje potentials were seen during sinus rhythm, and the optimal pace map was obtained with pace delay. During the VT, diastolic and systolic Purkinje potentials were simultaneously recorded at the same site. Ablation targeting the delayed potentials during sinus rhythm prolonged the time between QRS onset and the delayed potentials, and the VT no longer became inducible when the delayed potentials were completely eliminated. Left anterior fascicular VT develops in post-MI patients; ischemia-injured His-Purkinje system may be involved in the mechanism of the VT.
Abbreviations
- HPS:
-
His-Purkinje system
- MI:
-
myocardial infarction
- RBBB:
-
right bundle branch block
- RF:
-
radiofrequency
- VT:
-
ventricular tachycardia
References
Lopera, G., Stevenson, W. G., Soejima, K., Maisel, W. H., Koplan, B., Sapp, J. L., et al. (2004). Identification and ablation of three types of ventricular tachycardia involving the His-Purkinje system in patients with heart disease. Journal of Cardiovascular Electrophysiology, 15, 52–58.
Crijns, H. J., Smeets, J. L., Rodriguez, L. M., Meijer, A., & Wellens, H. J. (1995). Cure of interfascicular reentrant ventricular tachycardia by ablation of the anterior fascicle of the left bundle branch. Journal of Cardiovascular Electrophysiology, 6, 486–492.
Szumowski, L. J., Derejko, P., Sanders, P., Urbanek, P., Szufladowicz, E., Kepski, R., et al. (2005). Purkinje ventricular tachycardia after myocardial infarction. Heart Rhythm, 2(Suppl), S95 (abstract).
Bogun, F., Good, E., Reich, S., Elmouchi, D., Igic, P., Tschopp, D., et al. (2006). Role of Purkinje fibers in post-infarction ventricular tachycardia. Journal of the American College of Cardiology, 48, 2500–2507.
Reithmann, C., Hahnefeld, A., Remp, T., & Steinbeck, G. (2007). Ventricular tachycardia with participation of the left bundle-Purkinje system in patients with structural heart disease: Identification of slow conduction during sinus rhythm. Journal of Cardiovascular Electrophysiology, 18, 808–817.
Hayashi, M., Kobayashi, Y., Iwasaki, Y., Morita, N., Miyauchi, Y., Kato, T., et al. (2006). Novel mechanism of postinfarction ventricular tachycardia originating in surviving left posterior Purkinje fibers. Heart Rhythm, 3, 908–918.
Belhassen, B., Rotmensch, H. H., & Laniado, S. (1981). Response of recurrent sustained ventricular tachycardia to verapamil. British Heart Journal, 46, 679–682.
Ohe, T., Shimomura, K., Aihara, N., Kamakura, S., Matsuhisa, M., Sato, I., et al. (1988). Idiopathic sustained left ventricular tachycardia: clinical and electrophysiologic characteristics. Circulation, 77, 560–568.
Zipes, D. P., Foster, P. R., Troup, P. J., & Pedersen, D. H. (1979). Atrial induction of ventricular tachycardia: Reentry versus triggered automaticity. American Journal of Cardiology, 44, 1–8.
Josephson, M. E. (1993). Clinical cardiac electrophysiology: Techniques and interpretations (pp. 418–425, 2nd ed.). Philadelphia: Lea and Febiger.
Belhassen, B., Barash, E., Turgeman, Y., Rosenfeld, T., & Laniado, S. (1988). Recurrent sustained ventricular tachycardia solely responsive to verapamil in a patient with a remote myocardial infarction. Cardiology, 75, 294–300.
Ouyang, F., Cappato, R., Ernst, S., Goya, M., Volkmer, M., Hebe, J., et al. (2002). Electroanatomic substrate of idiopathic left ventricular tachycardia: unidirectional block and macroreentry within the Purkinje network. Circulation, 105, 462–469.
Nogami, A., Naito, S., Tada, H., Taniguchi, K., Okamoto, Y., Nishimura, S., et al. (2000). Demonstration of diastolic and presystolic Purkinje potentials as critical potentials in a macroreentry circuit of verapamil-sensitive idiopathic left ventricular tachycardia. Journal of the American College of Cardiology, 36, 811–823.
Fenoglio Jr, J. J., Pham, T. D., Harken, A. H., Horowitz, L. N., Josephson, M. E., & Wit, A. L. (1983). Recurrent sustained ventricular tachycardia: Structure and ultrastructure of subendocardial regions in which tachycardia originates. Circulation, 68, 518–533.
Friedman, P. L., Stewart, J. R., & Wit, A. L. (1973). Spontaneous and induced cardiac arrhythmias in subendocardial Purkinje fibers surviving extensive myocardial infarction in dogs. Circulation Research, 33, 612–626.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Morishima, I., Nogami, A., Tsuboi, H. et al. Verapamil-sensitive left anterior fascicular ventricular tachycardia associated with a healed myocardial infarction: changes in the delayed Purkinje potential during sinus rhythm. J Interv Card Electrophysiol 22, 233–237 (2008). https://doi.org/10.1007/s10840-008-9268-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10840-008-9268-4