Abstract
In 1952 I re-joined the Pharmacological Division of the Research Department of the Boots Co. in Nottingham UK to work on rheumatoid arthritis (RA) but with the distinct disadvantage that the Division was housed in a group of rambling buildings attached to a Victorian house. The Division had moved there at the beginning of World War II from the centre of Nottingham as a precaution against bombing - a wise move since part of the Research Department was destroyed in an air raid in 1941. Hence the first six years of my research was carried out under rather unfavourable conditions, for my laboratory was one of the two ‘front’ rooms of the house.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Harris, S. C. and Fosdick, L. S. (1952). Theoretical considerations of the mechanisms of antipyretic analgesia, NWU Bull. 53, 6.
Rainsford, K. D., Roberts, S. C. and Brown, S. (1997). Ibuprofen and paracetamol: relative safety in non-prescription doses, J. Pharm. And Pharmacol. 49, 345.
Sonasundaram, S., Hayllar, H., Rafi, S. et al (1995). The biochemical basis of non-steroidal anti-inflammatory drug-induced damage to the gastrointestinal tract: a review and a hypothesis, Scand. J. Gastroenterol. 30, 289.
Whitehouse, M. W. (1964). Some biochemical properties and a possible mode of action of anti-rheumatic drugs, Acta Rheum. Scand. Supp. 8, 5.
Wilhelmi, G. (1950). The anti-inflammatory effect of pyrazoles, particularly Irgapyrin, Schweiz. Med. Wschr. 80, 936.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Adams, S.S. Ibuprofen, the propionics and NSAIDs: Personal reflections over four decades. Inflammopharmacol 7, 191–197 (1999). https://doi.org/10.1007/s10787-999-0002-3
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10787-999-0002-3