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Sleep-disordered breathing in hospitalized patients with congestive heart failure: a concise review and proposed algorithm

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Abstract

Congestive heart failure (CHF) is the most common cause of hospital admission in the USA costing the taxpayers billions of dollars. Sleep-disordered breathing (SDB) is a common co-morbid condition associated with CHF with prevalence estimated to be 60–70%. Despite substantial evidence supporting the negative impact of SDB on CHF, the condition is underrecognized and undertreated. Patients admitted to the hospital with CHF and SDB are prime candidates for intervention with positive airway pressure (PAP) therapy as they form a “captive audience,” and timely intervention and education may mitigate sub-optimal outcomes. In conclusion, this review explores emerging data on the cost effectiveness and outcome of early intervention with PAP in hospitalized CHF patients.

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Author information

Authors and Affiliations

  1. Hartford Hospital, Hartford, CT, USA

    Ankit Gupta

  2. Harvard Medical School, Boston, MA, USA

    Stuart F. Quan

  3. Bad Oeynhausen, Germany

    Olaf Oldenburg

  4. UCSD, San Diego, CA, USA

    Atul Malhotra

  5. Albert Einstein Medical Center, Klein Building, Suite 363, 5501 Old York Road, Philadelphia, PA, 19141, USA

    Stuart F. Quan & Sunil Sharma

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  1. Ankit Gupta
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  2. Stuart F. Quan
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  3. Olaf Oldenburg
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  4. Atul Malhotra
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  5. Sunil Sharma
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Correspondence to Sunil Sharma.

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Conflict of interest

Dr. Sharma has received unrestricted research grants from ResMed Inc.

Dr. Quan has served as a consultant for Jazz Pharmaceuticals.

Dr. Malhotra is PI on NIH RO1 HL085188, K24 HL132105, and T32 HL134632 and co-investigator on R21 HL121794, RO1 HL 119201, and RO1 HL081823. As an Officer of the American Thoracic Society, Dr. Malhotra has relinquished all outside personal income since 2012. ResMed, Inc. provided a philanthropic donation to the UC San Diego in support of a sleep center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Drs. Ankit and Dr. Oldenburg have no conflicts of interest or financial ties to disclose.

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Gupta, A., Quan, S.F., Oldenburg, O. et al. Sleep-disordered breathing in hospitalized patients with congestive heart failure: a concise review and proposed algorithm. Heart Fail Rev 23, 701–709 (2018). https://doi.org/10.1007/s10741-018-9715-y

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