Skip to main content
Log in

Abdominal Surgery Affects Small Bowel Transit Time and Completeness of Capsule Endoscopy

  • ORIGINAL ARTICLE
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The aim of the study was to evaluate bowel dysmotility in patients with a history of abdominal surgery by measuring both gastric transit time and small bowel transit time during capsule endoscopy and assessing the completeness of the examination. The study included 26 patients who had undergone abdominal surgery (postoperative group) and 52 patients who had not (control group). The capsule reached the cecum in 50.0% of the postoperative group and 80.8% of the control group (P = 0.005). While there was no significant difference in gastric transit time between the two groups (P = 0.882), small bowel transit time was significantly longer in the postoperative group (338.3 ± 119.2 min) than in the control group (266.4 ± 110.8 min, P = 0.010). This is the first study to report that the small bowel transit time during capsule endoscopy is prolonged in patients who had a history of abdominal surgery, resulting in a lower frequency of complete examination.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Scapa E, Jacob H, Lewkowicz S, et al. Initial experience of wireless-capsule endoscopy for evaluating occult gastrointestinal bleeding and suspected small bowel pathology. Am J Gastroenterol. 2002;97:2776–2779. doi:10.1111/j.1572-0241.2002.07021.x.

    Article  PubMed  Google Scholar 

  2. Costamagna G, Shah SK, Riccioni ME, et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology. 2002;123:999–1005. doi:10.1053/gast.2002.35988.

    Article  PubMed  Google Scholar 

  3. Rey JF, Ladas S, Alhassani A, Kuznetsov K, ESGE Guidelines Committee. European Society of Gastrointestinal Endoscopy (ESGE): video capsule endoscopy: update to guidelines (May 2006). Endoscopy. 2006;38:1047–1053. doi:10.1055/s-2006-944874.

    Article  PubMed  CAS  Google Scholar 

  4. Caddy GR, Moran L, Chong AK, Miller AM, Taylor AC, Desmond PV. The effect of erythromycin on video capsule endoscopy intestinal-transit time. Gastrointest Endosc. 2006;63:262–266. doi:10.1016/j.gie.2005.07.043.

    Article  PubMed  Google Scholar 

  5. Sturniolo GC, Di Leo V, Vettorato MG, et al. Small bowel exploration by wireless capsule endoscopy: results from 314 procedures. Am J Med. 2006;119:341–347. doi:10.1016/j.amjmed.2005.08.029.

    Article  PubMed  Google Scholar 

  6. de Jonge WJ, van den Wijngaard RM, The FO, et al. Postoperative ileus is maintained by intestinal immune infiltrates that active inhibitory neural pathways in mice. Gastroenterology. 2003;125:1137–1147. doi:10.1016/S0016-5085(03)01197-1.

    Article  PubMed  Google Scholar 

  7. Uemura K, Tatewaki M, Harris MB, et al. Magnitude of abdominal incision affects the duration of postoperative ileus in rats. Surg Endosc. 2004;18:606–610. doi:10.1007/s00464-003-8161-6.

    Article  PubMed  CAS  Google Scholar 

  8. Triantafyllou K, Kalantzis C, Papadopoulos AA, et al. Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus. Dig Liver Dis. 2007;39:575–580. doi:10.1016/j.dld.2007.01.024.

    Article  PubMed  CAS  Google Scholar 

  9. Wei W, Ge ZZ, Lu H, Gao YJ, Hu YB, Xiao SD. Effect of mosapride on gastrointestinal transit time and diagnostic yield of capsule endoscopy. J Gastroenterol Hepatol. 2007;22:1605–1608. doi:10.1111/j.1440-1746.2007.05064.x.

    Article  PubMed  Google Scholar 

  10. Ben-Soussan E, Savoye G, Antonietti M, Ramirez S, Lerebours E, Ducrotté P. Factors that affect gastric passage of video capsule. Gastrointest Endosc. 2005;62:785–790. doi:10.1016/j.gie.2005.07.040.

    Article  PubMed  Google Scholar 

  11. Fukuda H, Tsuchida D, Koda K, Miyazaki M, Pappas TN, Takahashi T. Inhibition of sympathetic pathways restores postoperative ileus in the upper and lower gastrointestinal tract. J Gastroenterol Hepatol. 2007;22:1293–1299. doi:10.1111/j.1440-1746.2007.04915.x.

    Article  PubMed  Google Scholar 

  12. Eliakim R, Suissa A, Yassin K, Katz D, Fischer D. Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn’s disease—final report. Dig Liver Dis. 2004;36:519–522. doi:10.1016/j.dld.2004.03.011.

    Article  PubMed  CAS  Google Scholar 

  13. Mylonaki M, Fritscher-Ravens A, Swain P. Wireless capsule endoscopy: a comparison with push enteroscopy in patients with gastroscopy and colonoscopy negative gastrointestinal bleeding. Gut. 2003;52:1122–1126. doi:10.1136/gut.52.8.1122.

    Article  PubMed  CAS  Google Scholar 

  14. Hartmann D, Schilling D, Bolz G, et al. Capsule endoscopy versus push enteroscopy in patients with occult gastrointestinal bleeding. Z Gastroenterol. 2003;41:377–382. doi:10.1055/s-2003-37313.

    Article  PubMed  CAS  Google Scholar 

  15. Ell C, Remke S, May A, Helou L, Henrich R, Mayer G. The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding. Endoscopy. 2002;34:685–689. doi:10.1055/s-2002-33446.

    Article  PubMed  CAS  Google Scholar 

  16. Swain P, Fritscher-Ravens A. Role of video endoscopy in managing small bowel disease. Gut. 2004;53:1866–1875. doi:10.1136/gut.2003.035576.

    Article  PubMed  CAS  Google Scholar 

  17. Selby W. Complete small-bowel transit in patients undergoing capsule endoscopy: determining factors and improvement with metoclopramide. Gastrointest Endosc. 2005;61:80–85. doi:10.1016/S0016-5107(04)02462-9.

    Article  PubMed  Google Scholar 

  18. Hoog CM, Lindberg G, Sjoqvist U. Findings in patients with chronic intestinal dysmotility investigated by capsule endoscopy. BMC Gastroenterol. 2007;7:29. doi:10.1186/1471-230X-7-29.

    Article  PubMed  Google Scholar 

  19. Mair TS, Smith LJ. Survival and complication rates in 300 horses undergoing surgical treatment of colic. Part 3: Long-term complications and survival. Equine Vet J. 2005;37:310–314. doi:10.2746/0425164054529445.

    Article  PubMed  CAS  Google Scholar 

  20. Mochiki E, Asao T, Kuwano H. Gastrointestinal motility after digestive surgery. Surg Today. 2007;37:1023–1032. doi:10.1007/s00595-007-3525-5.

    Article  PubMed  Google Scholar 

  21. Majewski WD. Long-term outcome, adhesions, and quality of life after laparoscopic and open surgical therapies for acute abdomen: follow-up of a prospective trial. Surg Endosc. 2005;19:81–90. doi:10.1007/s00464-003-9333-0.

    Article  PubMed  CAS  Google Scholar 

  22. Kalff JC, Carlos TM, Schraut WH, Billiar TR, Simmons RL, Bauer AJ. Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus. Gastroenterology. 1999;117:378–387. doi:10.1053/gast.1999.0029900378.

    Article  PubMed  CAS  Google Scholar 

  23. Rondonotti E, Herrerias JM, Pennazio M, Caunedo A, Mascarenhas-Saravia M, de Franchis R. Complications, limitations and failures of capsule endoscopy: a review of 733 cases. Gastrointest Endosc. 2005;62:712–716. doi:10.1016/j.gie.2005.05.002.

    Article  PubMed  Google Scholar 

  24. Fireman Z, Kopelman Y, Fish L, Sternberg A, Scapa E, Mahaina E. Effect of oral purgatives on gastric and small bowel transit time in capsule endoscopy. Isr Med Assoc J. 2004;6:521–523.

    PubMed  Google Scholar 

  25. Dai N, Gubler C, Hengstler P, Meyenberger C, Bauerfeind P. Improved capsule endoscopy after bowel preparation. Gastrointest Endosc. 2005;61:28–31. doi:10.1016/S0016-5107(04)02444-7.

    Article  PubMed  Google Scholar 

  26. Benson MJ, Roberts JP, Wingate DL, et al. Small bowel motility following major intra-abdominal surgery: the effect of opiates and rectal cisapride. Gastroenterology. 1994;106:924–936.

    PubMed  CAS  Google Scholar 

  27. Fukuda H, Chen C, Mantyh C, Ludwig K, Pappas TN, Takahashi T. The herbal medicine, Dai-Kenchu-to, accelerates delayed gastrointestinal transit after the operation in rats. J Surg Res. 2006;131:290–295. doi:10.1016/j.jss.2005.09.018.

    Article  PubMed  Google Scholar 

  28. Tang SJ, Zanati S, Dubcenco E, et al. Capsule endoscopy regional transit abnormality: a sign of underlying small bowel pathology. Gastrointest Endosc. 2003;58:598–602.

    PubMed  Google Scholar 

  29. Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology. 2004;126:643–653. doi:10.1053/j.gastro.2003.11.057.

    Article  PubMed  Google Scholar 

  30. Baichi MM, Arifuddin RM, Mantry PS. Capsule endoscopy for obscure GI bleeding: therapeutic yield of follow-up procedures. Dig Dis Sci. 2007;52:1370–1375. doi:10.1007/s10620-006-9542-1.

    Article  PubMed  Google Scholar 

  31. Manabe N, Tanaka S, Fukumoto A, Nakao M, Kamino D, Chayama K. Double-balloon enteroscopy in patients with GI bleeding of obscure origin. Gastrointest Endosc. 2006;64:135–140. doi:10.1016/j.gie.2005.12.020.

    Article  PubMed  Google Scholar 

  32. Ohmiya N, Yano T, Yamamoto H, et al. Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy. Gastrointest Endosc. 2007;66(Suppl):S72–S77. doi:10.1016/j.gie.2007.05.041.

    Article  PubMed  Google Scholar 

  33. Endo H, Matsuhashi N, Inamori M, et al. Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding. BMC Gastroenterol. 2008;8:12. doi:10.1186/1471-230x-8-12.

    Article  PubMed  Google Scholar 

  34. Ueda K, Matteotti R, Assalia A, Gagner M. Comparative evaluation of gastrointestinal transit and immune response between laparoscopic and open gastrectomy in a porcine model. J Gastrointest Surg. 2006;10:39–45. doi:10.1016/j.gassur.2005.09.013.

    Article  PubMed  Google Scholar 

  35. Naitoh T, Garcia-Ruiz A, Vladisavljevic A, Matsuno S, Gagner M. Gastrointestinal transit and stress response after laparoscopic vs. conventional distal pancreatectomy in the canine model. Surg Endosc. 2002;16:1627–1630. doi:10.1007/s00464-002-0007-0.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hiroki Endo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Endo, H., Matsuhashi, N., Inamori, M. et al. Abdominal Surgery Affects Small Bowel Transit Time and Completeness of Capsule Endoscopy. Dig Dis Sci 54, 1066–1070 (2009). https://doi.org/10.1007/s10620-008-0467-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10620-008-0467-8

Keywords

Navigation