A new sterol, named 6β-methoxyergosta-7,9(11),22E-triene-3β,5α-diol (1), together with seven known ones (2–8), was isolated from the fruiting bodies of Haddowia longipes. Their structures were identified on the basis of 1D and 2D NMR spectroscopy as well as MS. The inhibitory activity of these isolates against acetylcholinesterase (AChE) showed that compound 1 exhibited weak inhibitory activity.
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Acknowledgment
This work was financially supported by the Natural Science Foundation of Hainan Province (219MS078), Natural Science Foundation of China (81973568), China Agriculture Research System (CARS-21), and Central Public-Interest Scientific Institution Basal Research Fund of Chinese Academy of Tropical Agricultural Sciences (17CXTD-15; 1630052016008).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2021, pp. 411–413.
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Zhang, SS., Ma, QY., Kong, FD. et al. Sterols from the Fruiting Bodies of Haddowia longipes. Chem Nat Compd 57, 482–484 (2021). https://doi.org/10.1007/s10600-021-03392-0
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DOI: https://doi.org/10.1007/s10600-021-03392-0