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Colutin, new antifungal isoflavan from Colutea armata

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Chemistry of Natural Compounds Aims and scope

A new isoflavan, colutin (1), has been isolated from the EtOAc soluble fraction of the MeOH extract of Colutea armata, along with three known compounds, sativan (2), isovestitol (3), and cinnamic acid (4), isolated for the first time from this species. Their structures were elucidated by spectroscopic techniques including two-dimensional NMR. Colutin (1) showed significant antifungal activity.

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Authors and Affiliations

  1. Department of Applied Chemistry, University of Karachi, 75270, Karachi, Pakistan

    Unber Shakeel, Farah Inamullah, Sadia Khan & Mehdi Hassan Kazmi

  2. H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, 75270, Karachi, Pakistan

    Itrat Fatima & Abdul Malik

  3. Department of Botany, Balochistan University, Sariab Road, Quetta, Pakistan

    Rasool Bakhsh Tareen

  4. Department of Microbiology, University of Karachi, 75270, Karachi, Pakistan

    Tanvir Abbas

Authors
  1. Unber Shakeel
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  2. Farah Inamullah
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  3. Itrat Fatima
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  4. Sadia Khan
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  5. Mehdi Hassan Kazmi
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  6. Abdul Malik
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  7. Rasool Bakhsh Tareen
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  8. Tanvir Abbas
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Corresponding author

Correspondence to Abdul Malik.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2016, pp. 529–531.

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Shakeel, U., Inamullah, F., Fatima, I. et al. Colutin, new antifungal isoflavan from Colutea armata . Chem Nat Compd 52, 611–614 (2016). https://doi.org/10.1007/s10600-016-1722-4

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  • DOI: https://doi.org/10.1007/s10600-016-1722-4

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