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A new E-ring γ-lactone pentacyclic triterpene from Lysimachia clethroides and its cytotoxic activities

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Chemistry of Natural Compounds Aims and scope

A new E-ring γ-lactone pentacyclic triterpene, 3β-myristoxyurs-12-en-19,28-olide, has been isolated from the chloroform extract of Lysimachia clethroides Duby, together with four known pentacyclic triterpenoid acids. The structures of the compounds were elucidated by comprehensive spectroscopic analyses. All of the compounds showed various degrees of cytotoxic activities in MTT assay.

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Acknowledgment

This research was funded by the National Sciences Foundation of China (No. 30873362) and the Pre-research Project of Soochow University. We express our thanks to Mrs. Li-Ping Shi, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, for the determination of NMR data.

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Authors and Affiliations

  1. College of Pharmacy, SooChow University, 215123, Suzhou, P. R. China

    Qiong-ming Xu, Yan-li Liu, Li-hua Tang & Shi-lin Yang

  2. Jiangxi College of Traditional Chinese Medicine, 330006, Nanchang, P. R. China

    Yu-lin Feng & Shi-lin Yang

Authors
  1. Qiong-ming Xu
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  2. Yan-li Liu
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  3. Yu-lin Feng
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  4. Li-hua Tang
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  5. Shi-lin Yang
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Corresponding author

Correspondence to Shi-lin Yang.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2012, pp. 536–538.

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Xu, Qm., Liu, Yl., Feng, Yl. et al. A new E-ring γ-lactone pentacyclic triterpene from Lysimachia clethroides and its cytotoxic activities. Chem Nat Compd 48, 597–600 (2012). https://doi.org/10.1007/s10600-012-0321-2

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  • DOI: https://doi.org/10.1007/s10600-012-0321-2

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