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UV-stability and UV-protective activity of alkaloids from the marine sponge Zyzzya fuliginosa

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Abstract

Alkaloids from the marine sponge Zyzzya fuliginosa damirones A (1) and B (2); makaluvamines H (3), C (4), G (5), and L (6); and zyzzyanones A (8) and B (9) were investigated for the ability to protect egg-cell membranes of the sea urchin Strongylocentrotus nudus from UV-radiation. Damirones, zyzzyanones, and tricyclic makaluvamines C (4) and H (3) exhibited the greatest membrane-protective activity. It was shown that makaluvamines G (5) and L (6) were converted by UV-irradiation into damirones A (1), B (2), tricyclic makaluvamines H (3), C (4), and zyzzyanones A (8) and B (9), respectively.

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Authors and Affiliations

  1. Pacific Institute of Bioorganic Chemistry, Far East Division, Russian Academy of Sciences, 690022, Vladivostok

    A. E. Makarchenko & N. K. Utkina

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  1. A. E. Makarchenko
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  2. N. K. Utkina
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–64, January–February, 2006.

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Makarchenko, A.E., Utkina, N.K. UV-stability and UV-protective activity of alkaloids from the marine sponge Zyzzya fuliginosa . Chem Nat Compd 42, 78–81 (2006). https://doi.org/10.1007/s10600-006-0040-7

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  • DOI: https://doi.org/10.1007/s10600-006-0040-7

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