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Chemical Constituents from the Hulls of Oryza sativa with Cytotoxic Activity

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Abstract

Five new compounds, orizaterpenol (1), orizaterpenoid (2), orizaterpenyl benzoate (3), orizanor-diterpenyl benzoate (4), and orizaditerpenyl benzoate (5), along with nine known compounds, were isolated and identified from the rice hulls of Oryza sativa. Their structures were elucidated with the help of different spectroscopic techniques. Orizaterpenol (1) and the known momilactone A (6) and B (7) were found to have cytotoxic effects against P388 murine leukaemia cells, while the other new and known compounds exhibited weak cytotoxicity.

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Authors and Affiliations

  1. Department of Applied Life Science, Konkuk University, Seoul, 143-701, South Korea

    I. M. Chung, S. J. Hahn & A. Ahmad

  2. Faculty of Pharmacy, Hamdard University, New Delhi, 110062, India

    M. Ali

  3. Department of Pharmacy, I. E. T., M. J. P. Rohilkhand University, Bareilly, 243006, India

    N. A. Siddiqui

  4. Department of Molecular Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, 143-701, Korea

    Y. H. Lim

Authors
  1. I. M. Chung
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  2. M. Ali
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  3. S. J. Hahn
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  4. N. A. Siddiqui
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  5. Y. H. Lim
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  6. A. Ahmad
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Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 146–151, March–April, 2005.

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Chung, I.M., Ali, M., Hahn, S.J. et al. Chemical Constituents from the Hulls of Oryza sativa with Cytotoxic Activity. Chem Nat Compd 41, 182–189 (2005). https://doi.org/10.1007/s10600-005-0108-9

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  • DOI: https://doi.org/10.1007/s10600-005-0108-9

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