This review considers methods for the synthesis of pyrimido[1,2-a]indoles and their ring-fused derivatives, covering publications from the last 10 years. Depending on the synthons used for assembling the target structure, three main approaches to the synthesis of pyrimido-[1,2-a]indoles can be distinguished: annulation of a pyrimidine ring to 2-aminoindoles, modification of other indole derivatives, and miscellaneous methods.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(10), 993–995
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Nikonov, I.L., Kopchuk, D.S., Zyryanov, G.V. et al. Synthesis of pyrimido[1,2-a]indoles (minireview). Chem Heterocycl Comp 57, 993–995 (2021). https://doi.org/10.1007/s10593-021-03012-3
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DOI: https://doi.org/10.1007/s10593-021-03012-3