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Recent approaches to the synthesis of 2H-azirines

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Chemistry of Heterocyclic Compounds Aims and scope

The most recent (2013–2018) synthetic approaches toward 2H-azirine derivatives are summarized and discussed. This minireview covers the latest examples on the synthesis of 2H-azirines that can be gathered in five distinct categories: the Neber approach, decomposition of vinyl azides, ring contraction of isoxazoles, oxidative cyclization of enamine derivatives, and radical addition/cyclization of alkynes.

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N. R. is thankful to SERB, India, for granting a postdoctoral fellowship. Financial support by “RUDN University Program 5-100” is gratefully acknowledged.

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Authors and Affiliations

  1. Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, B-3001, Leuven, Belgium

    Nagarajan Ramkumar, Upendra K. Sharma & Erik V. Van der Eycken

  2. RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia

    Leonid G. Voskressensky & Erik V. Van der Eycken

Authors
  1. Nagarajan Ramkumar
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  2. Leonid G. Voskressensky
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  3. Upendra K. Sharma
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  4. Erik V. Van der Eycken
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Correspondence to Erik V. Van der Eycken.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(9), 795–801

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Ramkumar, N., Voskressensky, L.G., Sharma, U.K. et al. Recent approaches to the synthesis of 2H-azirines. Chem Heterocycl Comp 55, 795–801 (2019). https://doi.org/10.1007/s10593-019-02539-w

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