Abstract
Methods have been developed for the synthesis of 2,3′-biquinolines, their 1′,4′-dihydro derivatives, 3-pyrid-2-ylquinolines, and 3-pyrazin-2-ylquinoline based on the interaction of hetarylethylenes and vinyl butyl ether with imidoyl chlorides and Vilsmeier complexes. Using the example of the synthesis of 3-hetarylquinolines and their dihydro derivatives the synthetic possibilities of the Vilsmeier method were shown for creating various bonds in different quinoline nuclei of the bisheterocyclic system.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1209–1215, August, 2008.
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Glushenko, T.P., Goncharov, V.I. & Aksenov, A.V. Investigations in 2,3′-biquinoline series 24. Synthesis of 3-hetarylquinolines and their 1,4-dihydro derivatives under conditions of the Vilsmeier reaction. Chem Heterocycl Comp 44, 973–978 (2008). https://doi.org/10.1007/s10593-008-0138-x
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DOI: https://doi.org/10.1007/s10593-008-0138-x