The combination of inherited and acquired factors of increased thrombosis complicates establishing the cause-effect relationships between mechanical injury and death during forensic medical examination. Morphometric parameters of the lung tissue and pulmonary vessels in isolated mechanical trauma under conditions of moderate hyperhomocysteinemia were studied in an experiment on laboratory animals. A regularity in changes of the morphometry parameters of the pulmonary vessels was found. Morphometric changes in the wall of pulmonary parenchyma veins can be used as an additional marker to assess the causal relationship between isolated mechanical injury and fatal complication in the form of pulmonary embolism.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Berezovsky DP, Majugin VY, Faleeva TG, Kurajan KM, Krainova NN, Habarova ОV, Voloshina GL, Varavva TA, Kornienko IV. Level of homocysteine at a trauma of the locomotor apparatus (experimental model on laboratory animals in conditions of methionine diets). Kuban. Nauch. Med. вестник. 2011;(5):24-29. Russian.
Pigolkin YuI, Nikityuk DB, Asanov AYu, Berezovskii DP, Bachurin SS, Sas’ko SS. Model of Moderate Hyperhomocis-teinemia Associated With Mechanical Injury: Dynamics of Morphometric Parameters of Microcirculatory Vessels. Bull. Exp. Biol. Med. 2019;167(4):533-535. doi: https://doi.org/10.1007/s10517-019-04567-0
Faleeva TG, Berezovskiy DP, Dodohova MA, Majugin VY, Varavva TA, Vechkanov EM, Kornienko IV. Morphometric features of extremity vessels of experimental animals at a trauma of the musculoskeletal system in the condition of moderate methionine induced homocysteinemia. Kuban. Nauch. Med. 2012;( 2):179-183.
Khlybova SV, Ipastova ID. The King of Dirty Tricks. Status Praesens. 2015;(4):101-109. Russian.
Meissner MH, Chandler WL, Elliott JS. Venous thromboembolism in trauma: a local manifestation of systemic hypercoagulability? J. Trauma. 2003;54(2):224-231.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 169, No. 5, pp. 657-660, May, 2020
Rights and permissions
About this article
Cite this article
Pigolkin, Y.I., Nikityuk, D.B., Kuznetsov, I.I. et al. Morphometric Parameters of the Lung Tissue in Isolated Musculoskeletal Injuries under Conditions of Moderate Hyperhomocysteinemia. Bull Exp Biol Med 169, 721–723 (2020). https://doi.org/10.1007/s10517-020-04964-w
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-020-04964-w