Drug penetration into bacterial biomembranes is one of the most important factors determining the efficiency of antibacterial therapy. Multicide, antibacterial drug, is a nanomolecule 1.3-2.0 nm in size, easily penetrating into staphylococcus biomembranes and causing rapid death of bacteria. The drug efficiency depends on its concentration and duration of exposure. Bacteria die as a result of cell wall perforation, which is associated with changes in its morphology and release of DNA from bacterial cell into the environment. Our results indicate the efficiency of primary damage to bacterial wall leading to elimination of biomembranes.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 163, No. 6, pp. 746-750, June, 2017
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Tetz, G.V., Artemenko, N.K., Yankovskii, G.M. et al. Effects of Multicide, Antibacterial Drug, on Staphylococcus Biomembranes. Bull Exp Biol Med 163, 780–784 (2017). https://doi.org/10.1007/s10517-017-3902-z
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DOI: https://doi.org/10.1007/s10517-017-3902-z