fMRI-EEG dynamics of brain activity in volunteers was studied during the course of EEG alpha-stimulation training (20 sessions). Twenty-three healthy men (20-35 years) were subjected to 3-fold mapping in a feedback loop (EEG alpha-rhythm biofeedback with acoustic reinforcement). This procedure was performed at the beginning, middle, and end of the course. During the first neurofeedback training session, deactivation (p<0.001) was found in the right angular gyrus, supramarginal, and superior temporal gyri, Brodmann area 39, and cerebellum. Activation (p<0.001) was observed in the medial frontal and cingulate gyri, motor areas of both hemispheres, and Brodmann area 32. During final (third) neurofeedback training session, we observed strong deactivation (p<0.05 with FDR) of zones responsible for spatial thinking and motor functions: left medial frontal and left medial temporal gyri; right postcentral, lingual, and superior frontal gyri; insula and right side of the cerebellum; and precuneus and cuneus (Brodmann areas 6, 9, 7, 31, 8, 13, and 22). Changes in the alpha wave power were most pronounced in the primary and secondary somatosensory cortex of the left hemisphere (Brodmann areas 2L and 5L).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Alekseeva MV, Balioz NV, Muravleva KB, Sapina EV, Bazanova OM. Alpha power voluntary increasing training for cognition enhancement study. Fiziol. Cheloveka. 2012;38(1):51-60.
Benedek M, Schickel RJ, Jauk E, Fink A, Neubauer AC. Alpha power increases in right parietal cortex reflects focused internal attention. Neuropsychologia. 2014;56:393-400.
Capotosto P, Babiloni C, Romani GL, Corbetta M. Restingstate modulation of α rhythms by interference with angular gyrus activity. J. Cogn. Neurosci. 2014;26(1):107-119.
de Munck JC, Gonçalves SI, Huijboom L, Kuijer JP, Pouwels PJ, Heethaar RM, Lopes da Silva FH. The hemodynamic response of the alpha rhythm: an EEG/fMRI study. Neuroimage. 2007;35(3):1142-1151.
Fink A, Benedek M. EEG alpha power and creative ideation. Neurosci. Biobehav. Rev. 2014;44:111-123.
Goldman RI, Stern JM, Engel J Jr, Cohen MS. Simultaneous EEG and fMRI of the alpha rhythm. Neuroreport. 2002;13(18):2487-2492.
Gonçalves SI, de Munck JC, Pouwels PJ, Schoonhoven R, Kuijer JP, Maurits NM, Hoogduin JM, Van Someren EJ, Heethaar RM, Lopes da Silva FH. Correlating the alpha rhythm to BOLD using simultaneous EEG/fMRI: inter-subject variability. Neuroimage. 2006;30(1):203-213.
Kay BP, Meng X, Difrancesco MW, Holland SK, Szaflarski JP. Moderating effects of music on resting state networks. Brain Res. 2012;1447:53-64.
Klimesch W. α-band oscillations, attention, and controlled access to stored information. Trends Cogn. Sci. 2012;16(12):606-617.
Laufs H, Holt JL, Elfont R, Krams M, Paul JS, Krakow K, Kleinschmidt A. Where the BOLD signal goes when alpha EEG leaves. Neuroimage. 2006;31(4):1408-1418.
Laufs H, Kleinschmidt A, Beyerle A, Eger E, Salek-Haddadi A, Preibisch C, Krakow K. EEG-correlated fMRI of human alpha activity. Neuroimage. 2003;19(4):1463-1476.
Meyer L, Obleser J, Friederici AD. Left parietal alpha enhancement during working memory-intensive sentence processing. Cortex. 2013;49(3):711-721.
Palva S, Palva JM. New vistas for alpha-frequency band oscillations. Trends Neurosci. 2007;30(4):150-158.
Zoefel B, Huster RJ, Herrmann CS. Neurofeedback training of the upper alpha frequency band in EEG improves cognitive performance. Neuroimage. 2011;54(2):1427-1431.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 5, pp. 560-565, May, 2016
Rights and permissions
About this article
Cite this article
Kozlova, L.I., Shtark, M.B., Mel’nikov, M.E. et al. EEG-fMRI Study of Alpha-Stimulation Neurobiofeedback Training Course. Bull Exp Biol Med 161, 623–628 (2016). https://doi.org/10.1007/s10517-016-3471-6
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-016-3471-6