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Parmacological Regulation of Erythropoietic Precursor Pool in Experimental Neuroses

  • Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
  • Published:
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Abstract

We studied the effect of bone marrow Thy 1,2+ cells on the growth of erythroid colonies and the role of monoamine in the regulation of proliferation and differentiation of erythroid precursor cells in experimental neuroses. Under conditions of conflict situation Thy 1,2+ cells stimulated the growth of erythropoietic precursors (directly and via interaction with adherent cells of the hemopoiesis-inducing environment). Under conditions of paradoxical sleep deprivation the absence of interaction between Thy 1,2+ cells and adherent bone marrow fraction disturbs erythroid colony formation. In experimental neuroses the state of erythropoietic precursors and secretory activity of elements of the hemopoiesis-inducing microenvironment are controlled by monoamines. The regulatory effect of monoamines is realized via adrenergic and erythropoietin-sensitive receptors on erythroid precursors and cells of the hemopoiesis-inducing microenvironment.

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REFERENCES

  1. E. D. Gol'dberg, A. M. Dygai, N. V. Provalova, et al., Role of Nervous System in Regulation of Hemopoiesis [in Russian], Tomsk (2004).

  2. E. D. Gol'dberg, A. M. Dygai, and I. A. Khlusov, Role of Autonomic Nervous System in Regulation of Hemopoiesis [in Russian], Tomsk (1997).

  3. E. D. Gol'dberg, A. M. Dygai, and V. P. Shakhov, Methods of Tissue Culture in Hematology [in Russian], Tomsk (1992).

  4. V. V. Zhdanov, S. G. Aksinenko, A. M. Dygai, and E. D. Gol'dberg, Byull. Eksp. Biol., 125, No. 5, 509–513 (1998).

    CAS  Google Scholar 

  5. Yu. M. Zakharov, Ross. Fiziol. Zh., 90, No. 8, 987–1000 (2004).

    Google Scholar 

  6. T. A. Klygul' and N. A. Krivopalov, Farmakol. Toksikol., No. 2, 241–244 (1966).

  7. M. V. Koval'zon, Vestn. Biol. Psychoatr, No. 3, 3–6 (2003).

  8. E. G. Skurikhin, A. M. Dygai, N. V. Provalova, et al., Byull. Eksp. Biol., 139, No. 5, 495–501 (2005).

    Google Scholar 

  9. S. H. Boyer, T. K. Bishop, O. Kogers, et al., Blood, 80, 2503–2512 (1992).

    CAS  PubMed  Google Scholar 

  10. C.-H. Dai, S. B. Krauntz, and K. M. Zsebo, Ibid., 78, 2493–2497 (1991).

    CAS  PubMed  Google Scholar 

  11. J. W. Fisher, Exp. Biol. Med (Maywood), 228, No. 1, 1–14 (2003).

    CAS  Google Scholar 

  12. D. Juovet, P. Vimont, F. Delorme, et al., Compt. Rend. Soc. Biol., 158, 756–759 (1964).

    Google Scholar 

  13. M. J. Koury and M. C. Bondurant, J. Cell Physiol., 137, 65–74 (1988).

    Article  CAS  PubMed  Google Scholar 

  14. M. J. Koury and M. C. Bondurant, Eur. J. Biochem., 210, 649–663 (1992).

    Article  CAS  PubMed  Google Scholar 

  15. A. Oda, M. Nishio, K. Sawada, J. Hematother. Stem Cell Res., 10, No. 5, 595–600 (2001).

    Article  CAS  PubMed  Google Scholar 

  16. J. L. Spivak, Oncology (Huntingt), 16, No. 9, Suppl. 10, 25–33 (2002).

    Google Scholar 

  17. J. L. Spivak, T. Pham, M. Isaaks, and W. D. Haukins, Blood, 77, 1228–1233 (1991).

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division, Russian Academy of Medical Sciences, Tomsk, Russia

    E. G. Skurikhin, N. V. Provalova, O. V. Pershina & M. Yu. Minakova

Authors
  1. E. G. Skurikhin
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  2. N. V. Provalova
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  3. O. V. Pershina
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  4. M. Yu. Minakova
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__________

Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 4, pp. 220–225, November, 2005

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Skurikhin, E.G., Provalova, N.V., Pershina, O.V. et al. Parmacological Regulation of Erythropoietic Precursor Pool in Experimental Neuroses. Bull Exp Biol Med 140, 621–626 (2005). https://doi.org/10.1007/s10517-006-0039-x

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  • DOI: https://doi.org/10.1007/s10517-006-0039-x

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