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Neuroprotective Effect of Cytoflavin during Compression Injury of the Spinal Cord

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Cytoflavin normalized energy metabolism, decreased the intensity of lipid peroxidation, and reactivated the antioxidant system in the spinal cord of rats with compression injury at the level of Th10–Th11. The neuroprotective effect of the test preparation manifested in normalization of hindlimb motor function and decrease in mortality rate of animals with spinal cord injury. Neuroprotective activity of cytoflavin was higher than that of Cerebrolysin.

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Authors and Affiliations

  1. Department of Neuropharmacology, Institute of Experimental Medicine, St. Petersburg, Russia

    V. V. Bul’on, N. N. Kuznetsova, E. N. Selina & N. S. Sapronov

  2. Polysan Research and Technological Pharmaceutical Company, St. Petersburg, Russia

    A. L. Kovalenko & L. E. Alekseeva

Authors
  1. V. V. Bul’on
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  2. N. N. Kuznetsova
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  3. E. N. Selina
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  4. A. L. Kovalenko
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  5. L. E. Alekseeva
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  6. N. S. Sapronov
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Corresponding author

Correspondence to V. V. Bul’on.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 139, No. 4, pp. 383–386, April, 2005

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Bul’on, V.V., Kuznetsova, N.N., Selina, E.N. et al. Neuroprotective Effect of Cytoflavin during Compression Injury of the Spinal Cord. Bull Exp Biol Med 139, 394–396 (2005). https://doi.org/10.1007/s10517-005-0303-5

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  • DOI: https://doi.org/10.1007/s10517-005-0303-5

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