Skip to main content

Advertisement

Log in

Antidiuretic hormone—V2-receptor—aquaporin-2 system in rat kidneys during acute inflammation

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Expression of antidiuretic hormone V2-receptor, water channel protein aquaporin-2, and cytokines interleukin-1β and interleukin-6 was studied in the kidneys of rats with acute inflammation produced by intraperitoneal injection of lipopolysaccharide in a dose of 250 µg/100 g. Reduced expression of aquaporin-2 and V2-receptor led to impairment of concentration capacity in the kidneys and decrease in urine osmolarity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. E. B. Liskina, V. V. Grinevich, O. V. Volkova, et al., Byull. Eksp. Biol. Med., 136, No. 2, 129–131 (2003).

    Google Scholar 

  2. G. Aguilera, Q. Pham, and C. Rabadan-Diehl, J. Neuroendocrinol., 6, No. 3, 299–304 (1994).

    Google Scholar 

  3. J. P. Burbach, S. M. Luckman, D. Murphy, and H. Gainer, Physiol. Rev., 81, 1197–1267 (2001).

    Google Scholar 

  4. V. Grinevich, X. M. Ma, J. P. Herman, et al., J. Neuroendocrinol., 13, No. 8, 711–723 (2001).

    Google Scholar 

  5. V. Grinevich, X. M. Ma, G. Jirikowski, et al., Ibid., 15, No. 2, 141–149 (2003).

    Google Scholar 

  6. M. A. Knepper, Am. J. Physiol., 272, F3–F12 (1997).

    Google Scholar 

  7. S. Nielsen, S. R. DiGiovanni, E. I. Christensen, et al., Proc. Natl. Acad. Sci. USA, 90, 11,663–11,667 (1993).

    Google Scholar 

  8. S. Rivest and N. Laflamme, J. Neuroendocrinol., 7, 501–525 (1995).

    Google Scholar 

  9. M. Yasui, D. Marples, R. Belusa, et al., Am. J. Physiol., 271, F461–F468 (1996).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. V. Misharin.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 11, pp. 511–516, November, 2004

Rights and permissions

Reprints and permissions

About this article

Cite this article

Misharin, A.V., Resnenko, A.B., Fidelina, O.V. et al. Antidiuretic hormone—V2-receptor—aquaporin-2 system in rat kidneys during acute inflammation. Bull Exp Biol Med 138, 452–456 (2004). https://doi.org/10.1007/s10517-005-0068-x

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-005-0068-x

Key Words

Navigation