Abstract
Cisgender men who have sex with transgender women face elevated risk for HIV, yet are understudied in prevention research. We conducted in-depth interviews with 19 men who have sex with transgender women in Baltimore, Maryland and Atlanta, Georgia to explore perspectives on HIV prevention. Participants used several strategies to reduce HIV risk: condoms, frequent HIV testing, communication about HIV status with partners, and limiting the types of sex acts performed. While condom use was inconsistent, it was preferred over pre-exposure prophylaxis, in part due to medical distrust. HIV self-testing was generally viewed unfavorably. Although most participants were referred to the study by their transgender women partners, they recommended reaching other men who have sex with transgender women in bars, nightclubs, online, and through social media. HIV prevention interventions should be inclusive of the needs and experiences of men who have sex with transgender women.
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Data Availability
Data used for analysis are in Table 2.
Code Availability
Qualitative codebook is available upon request.
References
Poteat T, Malik M, Wirtz AL, Cooney EE, Reisner S. Understanding HIV risk and vulnerability among cisgender men with transgender partners. Lancet HIV. 2020;7(3):e201–8.
Becasen JS, Denard CL, Mullins MM, Higa DH, Sipe TA. Estimating the prevalence of HIV and sexual behaviors among the US transgender population: a systematic review and meta-analysis, 2006–2017. Am J Public Health. 2018;109(1):e1–8.
Nemoto T, Bodeker B, Iwamoto M, Sakata M. Practices of receptive and insertive anal sex among transgender women in relation to partner types, sociocultural factors, and background variables. AIDS Care. 2014;26(4):434–40.
Wilson EC, Chen YH, Raad N, Raymond HF, Dowling T, McFarland W. Who are the sexual partners of transgender individuals? Differences in demographic characteristics and risk behaviours of San Francisco HIV testing clients with transgender sexual partners compared with overall testers. Sex Health. 2014;11(4):319–23.
Wilson EC, Santos GM, Raymond HF. Sexual mixing and the risk environment of sexually active transgender women: data from a respondent-driven sampling study of HIV risk among transwomen in San Francisco, 2010. BMC Infect Dis. 2014;14:430.
Gamarel KE, Reisner SL, Darbes LA, Hoff CC, Chakravarty D, Nemoto T, et al. Dyadic dynamics of HIV risk among transgender women and their primary male sexual partners: the role of sexual agreement types and motivations. AIDS Care. 2016;28(1):104–11.
Operario D, Nemoto T, Iwamoto M, Moore T. Risk for HIV and unprotected sexual behavior in male primary partners of transgender women. Arch Sex Behav. 2011;40(6):1255–61.
Reisner S, Mimiaga M, Bland SE, Driscoll MA, Cranston K, Mayer KH. Pathways to embodiment of HIV risk: black men who have sex with transgender partners, Boston, Massachusetts. AIDS Educ Prev. 2012;24(1):15–26.
Reisner SL, Gamarel KE, Nemoto T, Operario D. Dyadic effects of gender minority stressors in substance use behaviors among transgender women and their non-transgender male partners. Psychol Sex Orientat Gend Divers. 2014;1(1):63–71.
Restar AJ, Surace A, Ogunbajo A, Edeza A, Kahler C. The HIV-related risk factors of the cisgender male sexual partners of transgender women (MSTW) in the United States: a systematic review of the literature. AIDS Educ Prev. 2019;31(5):463–78.
Operario D, Burton J, Underhill K, Sevelius J. Men who have sex with transgender women: challenges to category-based HIV prevention. AIDS Behav. 2008;12(1):18–26.
Dangerfield DT, Smith LR, Williams J, Unger J, Bluthenthal R. Sexual positioning among men who have sex with men: a narrative review. Arch Sex Behav. 2017;46(4):869–84.
Baggaley RF, White RG, Boily M-C. HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention. Int J Epidemiol. 2010;39(4):1048–63.
Baggaley RF, Owen BN, Silhol R, Elmes J, Anton P, McGowan I, et al. Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis. Am J Reprod Immunol. 2018;80(5):e13039.
Health SFDoP. The HIV Epidemiology Annual Report. https://www.sfdph.org/dph/comupg/oprograms/HIVepiSec/HIVepiSecReports.asp (2014). Accessed 1 July 2016.
Henny KD, Jeffries WL. Ending the HIV epidemic in the United States must start with the South. AIDS Behav. 2019;23(3):221–3.
Centers for Disease Control and Prevention. HIV Surveillance Report. 2018. (Updated); vol. 31 2020 [updated May 2020November 22, 2020]. http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html.
Siegler AJ, Mouhanna F, Giler RM, Weiss K, Pembleton E, Guest J, et al. The prevalence of pre-exposure prophylaxis use and the pre-exposure prophylaxis-to-need ratio in the fourth quarter of 2017. US Ann Epidemiol. 2018;28(12):841–9.
Centers for Disease Control and Prevention.HIV Surveillance Report. (Updated); vol.31. Published May 2020. http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html (2018). Accessed 5 Nov 2020.
Salazar LF, Crosby RA, Jones J, Kota K, Hill B, Masyn KE. Contextual, experiential, and behavioral risk factors associated with HIV status: a descriptive analysis of transgender women residing in Atlanta Georgia. Int J STD AIDS. 2017;28(11):1059–66.
Sherman SG, Park JN, Galai N, Allen ST, Huettner SS, Silberzahn BE, et al. Drivers of HIV infection among cisgender and transgender female sex worker populations in Baltimore city: results from the SAPPHIRE study. J Acquir Immune Defic Syndr. 2019;80(5):513–21.
Steehler K, Siegler AJ. Bringing HIV self-testing to scale in the United States: a review of challenges, potential solutions, and future opportunities. J Clin Microbiol. 2019. https://doi.org/10.1128/JCM.00257-19.
Desai M, Field N, Grant R, McCormack S. Recent advances in pre-exposure prophylaxis for HIV. BMJ. 2017;359:j5011.
Reif S, Whetten K, Wilson E, Gong W. HIV/AIDS epidemic in the South reaches crisis proportions in last decade. https://southernaids.files.wordpress.com/2011/10/research-report-final-revised10-26-121.pdf (2011). Accessed 22 Jan 2021.
Reif S, Geonnotti KL, Whetten K. HIV infection and AIDS in the deep south. Am J Public Health. 2006;96(6):970–3.
Whetten K, Reif S. Overview: HIV/AIDS in the deep south region of the United States. AIDS Care. 2006;18(S1–5):1p.
Harshbarger D, Perry AM. The rise of black majority cities. https://www.brookings.edu/research/the-rise-of-black-majority-cities/ (2019). Accessed 29 Nov 2020.
Scott D. Stress and coping amongst cisgender male partners of transgender women. Cult Health Sex. 2020. https://doi.org/10.1080/13691058.2020.1825814.
Doyle L, McCabe C, Keogh B, Brady A, McCann M. An overview of the qualitative descriptive design within nursing research. J Res Nurs. 2019;25(5):443–55.
Sandelowski M. What’s in a name? Qualitative description revisited. Res Nurs Health. 2010;33(1):77–84.
Bradshaw C, Atkinson S, Doody O. Employing a qualitative description approach in health care research. Glob Qual Nurs Res. 2017;4:2333393617742282.
Lambert VA, Lambert CE. Editorial: qualitative descriptive research: an acceptable design. Pac Rim Int J Nurs Res. 2012;16(4):255–6.
Sandelowski M. Focus on research methods. Whatever happened to qualitative description? Res Nurs Health. 2000;23(4):334–40.
Gibbs GR. Thematic coding and categorizing. In: Gibbs GR, editor. Analyzing qualitative data. London: SAGE Publications Ltd; 2007. p. 38–55.
Guba EG. Criteria for assessing the trustworthiness of naturalistic inquiries. ECTJ. 1981;29(2):75.
Rodgers BL, Cowles KV. The qualitative research audit trail: a complex collection of documentation. Res Nurs Health. 1993;16(3):219–26.
Elopre L, McDavid C, Brown A, Shurbaji S, Mugavero MJ, Turan JM. Perceptions of HIV pre-exposure prophylaxis among young, black men who have sex with men. AIDS Patient Care STDs. 2018;32(12):511–8.
Cahill S, Taylor SW, Elsesser SA, Mena L, Hickson D, Mayer KH. Stigma, medical mistrust, and perceived racism may affect PrEP awareness and uptake in black compared to white gay and bisexual men in Jackson, Mississippi and Boston. Mass AIDS Care. 2017;29(11):1351–8.
Jaiswal J. Whose responsibility is it to dismantle medical mistrust? Future directions for researchers and health care providers. Behav Med. 2019;45(2):188–96.
Byrd WM, Clayton LA. Race, medicine, and health care in the United States: a historical survey. J Natl Med Assoc. 2001;93(3 Suppl):11S-34S.
Dehon E, Weiss N, Jones J, Faulconer W, Hinton E, Sterling S. A systematic review of the impact of physician implicit racial bias on clinical decision making. Acad Emerg Med. 2017;24(8):895–904.
Williams DR, Cooper LA. Reducing racial inequities in health: using what we already know to take action. Int J Environ Res Public Health. 2019;16(4):606.
Bowleg L, Burkholder GJ, Massie JS, Wahome R, Teti M, Malebranche DJ, et al. Racial discrimination, social support, and sexual HIV risk among black heterosexual men. AIDS Behav. 2013;17(1):407–18.
Washington HA. Medical apartheid: the dark history of medical experimentation on black Americans from colonial times to the present. New York: Doubleday Books; 2006.
Hardeman RR, Medina EM, Kozhimannil KB. Structural racism and supporting black lives—the role of health professionals. N Engl J Med. 2016;375(22):2113–5.
Metzl JM, Roberts DE. Structural competency meets structural racism: race, politics, and the structure of medical knowledge. AMA J Ethic. 2014;16(9):674–90.
Frye V, Wilton L, Hirshfied S, Chiasson MA, Usher D, Lucy D, et al. “Just because it’s out there, people aren’t going to use it.” HIV self-testing among young, black MSM, and transgender women. AIDS Patient Care STDs. 2015;29(11):617–24.
Bowleg L, Del Rio-Gonzalez AM, Holt SL, Perez C, Massie JS, Mandell JE, et al. Intersectional epistemologies of ignorance: how behavioral and social science research shapes what we know, think we know, and don’t know about U.S. black men’s sexualities. J Sex Res. 2017;54(4–5):577–603.
Bowleg L, Mingo M, Massie JS. “The skill is using your big head over your little head”: what black heterosexual men say they know, want, and need to prevent HIV. Am J Men’s Health. 2013;7(4 Suppl):31s–42s.
Tompkins AB. “There’s no chasing involved”: cis/trans relationships, “tranny chasers,” and the future of a sex-positive trans politics. J Homosex. 2014;61(5):766–80.
Came H, Griffith D. Tackling racism as a “wicked” public health problem: enabling allies in anti-racism praxis. Soc Sci Med. 2018;199:181–8.
Lucey CR, Saguil A. The consequences of structural racism on MCAT scores and medical school admissions: the past is prologue. Acad Med. 2020;95(3):351–6.
Acknowledgements
We are grateful to Monica Stevens who inspired this research study and contributed to our thinking about the relationships between transgender women and men who have sex with transgender women. We appreciate Darius Scott who supported data coding and Bennet Gosiker who assured the accuracy of the transcripts.
Funding
The study was funded by the National Institutes of Mental Health (R25MH067127).
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TP conceived of and designed the study, collected data, contributed to analysis, and wrote the initial draft of the paper. EC collected data and contributed to analysis. MM contributed to analysis and editing. AR contributed to analysis and editing. DTD contributed to analysis and editing. JW collected data, contributed to analysis and editing.
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TP, MM, and JW have received research funding support to their institution from ViiV Healthcare. AR and EC declare no conflicts of interest.
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This study was approved by the Johns Hopkins Bloomberg School of Public Health Institutional Review Board.
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All participants provided verbal informed consent.
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Poteat, T., Cooney, E., Malik, M. et al. HIV Prevention Among Cisgender Men Who have Sex with Transgender Women. AIDS Behav 25, 2325–2335 (2021). https://doi.org/10.1007/s10461-021-03194-z
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DOI: https://doi.org/10.1007/s10461-021-03194-z