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Restoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To study morphologically and functionally the prognosis of damaged outer segments of the foveal photoreceptor layer in eyes with resolved central serous chorioretinopathy (CSC).

Methods

We studied retrospectively the medical records of 70 patients (74 eyes) with resolved CSC. Optical coherence tomography was used to detect the junctions between inner and outer segments of the photoreceptors (IS/OS) as a hallmark of the integrity of the outer photoreceptor layer.

Results

In 53 eyes (71.6%), the IS/OS line was clearly detected beneath the fovea immediately after resolution of the retinal detachment, with good visual acuity (VA). In the remaining 21 eyes (28.4%), however, the foveal IS/OS line could not be detected shortly after resolution of CSC, and VA was variable, ranging from 0.1 to 1.5 (median, 0.9). Of these 21 eyes, 15 had a follow-up examination with OCT, and in four the foveal IS/OS line was not detected at the follow-up and vision in these eyes remained poor. However, nine eyes showed recovery of the foveal IS/OS line during follow-up, and these eyes had substantial visual recovery.

Conclusions

Immediately after resolution of active CSC, although the IS/OS line cannot be detected beneath the fovea, it often shows restoration over time, with visual recovery, though in some eyes no restoration takes place and the prognosis remains poor.

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Authors and Affiliations

  1. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Yumiko Ojima, Akitaka Tsujikawa, Kenji Yamashiro, Sotaro Ooto, Hiroshi Tamura & Nagahisa Yoshimura

  2. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan

    Akitaka Tsujikawa

Authors
  1. Yumiko Ojima
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  2. Akitaka Tsujikawa
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  3. Kenji Yamashiro
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  4. Sotaro Ooto
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  5. Hiroshi Tamura
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  6. Nagahisa Yoshimura
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Corresponding author

Correspondence to Akitaka Tsujikawa.

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Ojima, Y., Tsujikawa, A., Yamashiro, K. et al. Restoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy. Jpn J Ophthalmol 54, 55–60 (2010). https://doi.org/10.1007/s10384-009-0766-4

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  • DOI: https://doi.org/10.1007/s10384-009-0766-4

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