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Ionic Liquid-Based Ultrasound-Assisted Extraction of Chlorogenic Acid from Lonicera japonica Thunb

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Abstract

Hydrophilic ionic liquid of [BMIM][BF4] was successfully applied for the ultrasound-assisted extraction (UAE) of hydrophilic chlorogenic acid from Lonicera japonica Thunb. To explore this extraction procedure, the corresponding extraction parameters including the sample size, [BMIM][BF4] concentration, pH, extraction temperature, ultrasonic power and extraction time were investigated. The results revealed that the [BMIM][BF4]-based UAE efficiency of chlorogenic acid was higher than that of the ethanol-based UAE and the traditional refluent ethanol extraction. And the study on the method reliability further confirmed that the [BMIM][BF4]-based UAE is suitable for the effective extraction of chlorogenic acid from honeysuckle.

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References

  1. China Pharmacopoeia Committee (2005) Pharmacopoeia of the People’s Republic of China, First Division, 2005 ed., China Chemical Industry Press, Beijing, 152

  2. Zhang B, Yang RY, Liu CZ (2008) Sep Purif Technol 62:480–483

    Article  CAS  Google Scholar 

  3. Xiang ZN, Ning ZX (2008) Food Sci Technol 41:1189–1203

    CAS  Google Scholar 

  4. Zhang B, Yang RY, Zhao Y, Liu CZ (2008) J Chromatogr B 867:253–258

    Article  CAS  Google Scholar 

  5. Wang ZL, Wang JH, Sun YS, Li SB, Wang HZ (2008) Sep Purif Technol 63:721–724

    Article  CAS  Google Scholar 

  6. Hu FL, Deng CH, Liu Y, Zhang XM (2009) Talanta 77:1299–1303

    Article  CAS  Google Scholar 

  7. Niu JG, Qiu HD, Li J, Liu X, Jiang SX (2009) Chromatographia 69:1093–1096

    Article  CAS  Google Scholar 

  8. Sun XQ, Peng B, Ji Y, Chen J, Li DQ (2008) Sep Purif Technol 63:61–68

    Article  CAS  Google Scholar 

  9. Zhou QX, Bai HH, Xie GH, Xiao JP (2008) J Chromatogr A 1177:43–49

    Article  CAS  Google Scholar 

  10. Fan J, Fan YC, Pei YC, Wu K, Wang JJ, Fan MH (2008) Sep Purif Technol 61:324–331

    Article  CAS  Google Scholar 

  11. Du FY, Xiao XH, Luo XJ, Li GK (2009) Talanta 78:1177–1184

    Article  CAS  Google Scholar 

  12. Du FY, Xiao XH, Li GK (2007) J Chromatogr A 1140:56–62

    Article  CAS  Google Scholar 

  13. Cao XJ, Ye XM, Lu YB, Yu Y, Mo WM (2009) Anal Chim Acta 640:47–51

    Article  CAS  Google Scholar 

  14. Wang LJ, Weller CL (2006) Trends Food Sci Technol 17:300–312

    Article  CAS  Google Scholar 

  15. Li SQ, Cai S, Hu W, Chen H, Liu HL (2009) Spectrochim Acta Part B 64:666–671

    Article  Google Scholar 

  16. Gao R, Zheng Q, Gong T, Fu Y, Deng L, Zhang ZR (2007) J Pharm Biomed Anal 43:335–340

    Article  CAS  Google Scholar 

  17. Yan SK, Luo GA, Wang YM, Cheng YY (2006) J Pharm Biomed Anal 40:889–895

    Article  CAS  Google Scholar 

  18. Li ZB, Huang DN, Tang ZX, Deng CH, Zhang XM (2010) Talanta 82:1181–1185

    Article  CAS  Google Scholar 

  19. Zhang J, Chen M, Ju WZ, Liu SJ, Xu MJ, Chu JH, Wu T (2010) J Pharm Biomed Anal 51:685–690

    Article  CAS  Google Scholar 

  20. Yu YY, Zhang W, Cao SW (2007) Chin J Anal Chem 35:1726–1730

    Article  CAS  Google Scholar 

  21. Serpone N, Colarusso P (1994) Res Chem Intermed 20:635–679

    Article  CAS  Google Scholar 

  22. Lu YB, Ma WY, Hu RL, Dai XJ, Pan YJ (2008) J Chromatogr A 120:42–46

    Article  Google Scholar 

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Authors and Affiliations

  1. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, 100083, China

    Lijin Zhang & Fang Chen

  2. Department of Food Science, Tianjin Agricultural University, Tianjin, 300384, China

    Lijin Zhang, Jinfu Liu, Pingping Zhang, Shijie Yan & Xinyi He

Authors
  1. Lijin Zhang
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  2. Jinfu Liu
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  3. Pingping Zhang
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  4. Shijie Yan
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  5. Xinyi He
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  6. Fang Chen
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Corresponding author

Correspondence to Fang Chen.

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Zhang, L., Liu, J., Zhang, P. et al. Ionic Liquid-Based Ultrasound-Assisted Extraction of Chlorogenic Acid from Lonicera japonica Thunb. Chromatographia 73, 129–133 (2011). https://doi.org/10.1007/s10337-010-1828-y

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  • DOI: https://doi.org/10.1007/s10337-010-1828-y

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