Abstract
l-lactate is a major analyte in the food industry, bioprocess engineering, sports medicine and clinical care unit. l-lactate detection by standard analytical techniques is expensive, time-consuming and difficult for in situ studies. Therefore, selective l-lactate biosensors are developed to overcome the current challenges of food industries and biological sectors. High-throughput nanobiosensors appear promising for on-site detection of lactate in industrial- and laboratory-scale applications. Here, we review principles of lactate sensing techniques and trends in transduction approaches. We discuss nanomaterials, merits and demerits of enzyme-based lactate analysis and commercial testing kits. We present also non-enzymatic nanobiosensors.
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This review article was supported by The National Institute of Food Technology Entrepreneurship and Management (NIFTEM), set up by Ministry of Food Processing Industries (MOFPI), Government of India, Kundli, Sonipat district, Haryana, under Delhi NCR.
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GR designed the manuscript, wrote the initial and final drafts, performed preliminary data analysis, composed the manuscript, and conducted the initial review. NK provided the conceptual framework and major headings for the review. VKM added and edited the tables, figures and whole manuscript as per journal guidelines. Dr. PMK supervised the project and edited the final version of the manuscript and evaluated and amended drafts.
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Rattu, G., Khansili, N., Maurya, V.K. et al. Lactate detection sensors for food, clinical and biological applications: a review. Environ Chem Lett 19, 1135–1152 (2021). https://doi.org/10.1007/s10311-020-01106-6
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DOI: https://doi.org/10.1007/s10311-020-01106-6