Skip to main content
Log in

Automatic Active Contour-Based Segmentation and Classification of Carotid Artery Ultrasound Images

  • Published:
Journal of Digital Imaging Aims and scope Submit manuscript

Abstract

In this paper, we present automatic image segmentation and classification technique for carotid artery ultrasound images based on active contour approach. For early detection of the plaque in carotid artery to avoid serious brain strokes, active contour-based techniques have been applied successfully to segment out the carotid artery ultrasound images. Further, ultrasound images might be affected due to rotation, scaling, or translational factors during acquisition process. Keeping in view these facts, image alignment is used as a preprocessing step to align the carotid artery ultrasound images. In our experimental study, we exploit intima–media thickness (IMT) measurement to detect the presence of plaque in the artery. Support vector machine (SVM) classification is employed using these segmented images to distinguish the normal and diseased artery images. IMT measurement is used to form the feature vector. Our proposed approach segments the carotid artery images in an automatic way and further classifies them using SVM. Experimental results show the learning capability of SVM classifier and validate the usefulness of our proposed approach. Further, the proposed approach needs minimum interaction from a user for an early detection of plaque in carotid artery. Regarding the usefulness of the proposed approach in healthcare, it can be effectively used in remote areas as a preliminary clinical step even in the absence of highly skilled radiologists.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Kamel M, Campilho A, Abdel-Dayem A, El-Sakka M: Fuzzy C: Means Clustering for Segmenting Carotid Artery Ultrasound Images. In: Image Analysis and Recognition. Berlin: Springer, 2007, 935–948

  2. Kamel M, Campilho A, Abdel-Dayem AR, El-Sakka MR: Carotid Artery Ultrasound Image Segmentation Using Fuzzy Region Growing. In: Image Analysis and Recognition. Berlin: Springer, 2005, 869–878

  3. Ceccarelli M, De Luca N, Morganella A: An Active Contour Approach to Automatic Detection of the Intima-Media Thickness. IEEE International Conference on Acoustics, Speech and Signal Processing ICASSP Toulouse, II-II, 2006

  4. Gustavsson T, Quan L, Wendelhag I, Wikstrand J: A dynamic programming procedure for automated ultrasonic measurement of the carotid artery. IEEE, Computers in Cardiology Bethesda, MD, USA, 1994, 297–300

  5. Rui R, Aur, Lio C, Jorge S, Elsa A, Rosa S: Segmentation of the carotid intima-media region in B-mode ultrasound images. Image Vision Comput 28:614–625, 2010

    Article  Google Scholar 

  6. Moursi SG, Sakka MRE: Semi-automatic snake based segmentation of carotid artery ultrasound images. Communications of the Arab Computer Society (ACS), 2009, vol. 2, 1–32

  7. Hassan M, Chaudhry A, Khan A, Riaz S: An Optimized Fuzzy C-Means Clustering with Spatial Information for Carotid Artery Image Segmentation. IEEE, 8th IBCAST Islamabad, 2011

  8. Chaudhry A, Hassan M, Khan A, Kim JY: Image Clustering Using Improved Spatial Fuzzy C-Means. ICUIMC, Kuala Lumpur, 2012

  9. Chaudhry A, Hassan M, Khan A, Kim J, Tuan T: Automatic Segmentation and Decision Making of Carotid Artery Ultrasound Images. In: Intelligent Autonomous Systems 12. Berlin: Springer, 2012, 185–196

  10. Hassan M, Chaudhry A, Khan A, Kim JY: Carotid artery image segmentation using modified spatial fuzzy c-means and ensemble clustering. Comput. Methods Programs Biomed. 2012 108(3):1261–1276. doi:10.1016/j.cmpb.2012.08.011

  11. Gonzalez RC, Woods RE: Digital Image Processing. Pearson Prentice Hall, Upper Saddle River, 2008

    Google Scholar 

  12. Pham DL, Xu C, Prince JL: A Survey of Current Methods in Medical Image Segmentation. In: Annual Review of Biomedical Engineering, 2000, 315–338

  13. Otsu N: A threshold selection method from gray-level histograms. IEEE Transactions on Systems, Man., and Cybernetics 9:62–66, 1979

    Article  Google Scholar 

  14. Kass M, Witkin A, Terzopoulos D: Snakes: active contour models. International Journal of Computer Vision 1:321–331, 1988

    Article  Google Scholar 

  15. Liang J, McInerny T, Terzopoulos D: United Snakes. IEEE, Int. Conf. Computer Vision, 1999, 933–940

  16. Brigger P, Hoeg J, Unser M: B-spline snakes: a flexible tool for parametric contour detection. IEEE Transaction on Image Processing 9:1484–1496, 2000

    Article  CAS  Google Scholar 

  17. Weruaga L, Verdu R, Morales J: Frequency domain formulation of active parametric deformable models. IEEE Transaction on Pattern Analysis and Machine Intelligence 26:1568–1578, 2004

    Article  Google Scholar 

  18. Unser M Splines: A perfect fit for medical imaging. Progress in Biomedical Optics and Imaging, 2002

  19. Cristianini N, Taylor JS: An Introduction to Support Vector Machines and Other Kernel-Based Learning Methods. Cambridge University Press, Cambridge, 2000

    Book  Google Scholar 

  20. Minghao P, Heon Gyu L, Couchol P, Keun Ho R: A data mining approach for dyslipidemia disease prediction using carotid arterial feature vectors. IEEE, 2nd International Conference on Computer Engineering and Technology (ICCET) Chengdu, V2-171-V2-175, 2010

  21. Chih-Chung C, Chih-Jen L: LIBSVM: a library for support vector machines. ACM Trans Intell Syst Technol 2:1–27, 2011

    Article  Google Scholar 

  22. Altman DG: Statistics notes: diagnostic tests 2: predictive values. BMJ 309:102.1, 1994

    Google Scholar 

  23. Park SH, Goo JM, Jo C-H: Receiver operating characteristic (ROC) curve: practical review for radiologists. Korean J Radiol 5(1):11–18, 2004

    Article  PubMed  Google Scholar 

  24. Santhiyakumari N, Rajendran P, Madheswaran M: Medical decision-making system of ultrasound carotid artery intima–media thickness using neural networks. J Digital Imaging 24:1112–1125, 2011

    Article  CAS  Google Scholar 

  25. Pal SK, Mitra P: Pattern Recognition Algorithms for Data Mining: Scalability, Knowledge Discovery, and Soft Granular Computing. Chapman & Hall, London, 2004

    Book  Google Scholar 

  26. Specht DF: Probabilistic neural networks and the polynomial Adaline as complementary techniques for classification. IEEE Transaction on Neural Networks 1:111–121, 1990

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This research work is supported by the Higher Education Commission of Pakistan under the indigenous Ph.D. scholarship program (17-5-4(Ps4-078)/HEC/Sch/2008/) and BK21 Postdoc Fellowship Program of South Korea. The authors would like to extend their thanks to Shifa International Hospital, Islamabad for providing data and technical support to complete this research work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Asmatullah Chaudhry.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chaudhry, A., Hassan, M., Khan, A. et al. Automatic Active Contour-Based Segmentation and Classification of Carotid Artery Ultrasound Images. J Digit Imaging 26, 1071–1081 (2013). https://doi.org/10.1007/s10278-012-9566-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10278-012-9566-3

Keywords

Navigation