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Patient-reported outcome and cognitive measures to be used in vascular and brain tumor surgery: proposal for a minimum set

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Abstract

Background

The standardization of outcome measures is needed for comparing studies and using common measures in clinical practice. We aimed to identify cognitive and patient-reported outcomes and timing of assessment for glioma, meningioma, and vascular surgery.

Method

A consensus study was conducted. Participants selected cognitive and patient-reported measures among a list of instruments identified through a literature search.

Results

Seventeen cognitive tests for the glioma and meningioma’s evaluation, 8 for the vascular diseases, and one questionnaire on quality of life and one on emotional distress were identified. The timing of outcome assessment selected was before surgery, at discharge, and after 3 and 12 months for glioma; before surgery and after 3 months for meningioma; before surgery, at discharge, and after 6 months for vascular diseases.

Conclusion

The identification of common outcome measures is the first step toward a shared data collection improving the quality and comparability of future studies.

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References

  1. Kirkham JJ, Dwan KM, Altman DG et al (2010) The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ 340:365. https://doi.org/10.1136/bmj.c365

    Article  Google Scholar 

  2. Macefield RC, Jacobs M, Korfage IJ et al (2014) Developing core outcomes sets: methods for identifying and including patient-reported outcomes (PROs). Trials 15:49. https://doi.org/10.1186/1745-6215-15-49

    Article  PubMed  PubMed Central  Google Scholar 

  3. Grinnon ST, Miller K, Marler JR et al (2012) National Institute of Neurological Disorders and Stroke Common Data Element Project-approach and methods. Clin Trials 9(3):322–329. https://doi.org/10.1177/1740774512438980

    Article  PubMed  PubMed Central  Google Scholar 

  4. Williamson PR, Altman DG, Blazeby JM et al (2012) Developing core outcome sets for clinical trials: issues to consider. Trials 13:132. https://doi.org/10.1186/1745-6215-13-132

    Article  PubMed  PubMed Central  Google Scholar 

  5. Papagno C, Casarotti A, Comi A et al (2012) Measuring clinical outcomes in neuro-oncology. A battery to evaluate low-grade gliomas (LGG). J Neurooncol 108(2):269–275. https://doi.org/10.1007/s11060-012-0824-5

    Article  PubMed  Google Scholar 

  6. Rofes A, Mandonnet E, Godden J et al (2017) Survey on current cognitive practices within the European Low-Grade Glioma Network: towards a European assessment protocol. Acta Neurochir (Wien) 159(7):1167–1178. https://doi.org/10.1007/s00701-017-3192-2

    Article  Google Scholar 

  7. Yoshii Y, Tominaga D, Sugimoto K et al (2008) Cognitive function of patients with brain tumor in pre- and postoperative stage. Surg Neurol 69(1):51–61. https://doi.org/10.1016/j.surneu.2007.07.064

    Article  PubMed  Google Scholar 

  8. Dijkstra M, Van Nieuwenhuizen D, Stalpers LJA et al (2009) Late neurocognitive sequelae in patients with WHO grade I meningioma. J Neurol Neurosurg Psychiatry 80(8):910–915. https://doi.org/10.1136/jnnp.2007.138925

    Article  CAS  PubMed  Google Scholar 

  9. Waagemans ML, Van Nieuwenhuizen D, Dijkstra M et al (2011) Long-term impact of cognitive deficits and epilepsy on quality of life in patients with low-grade meningiomas. Neurosurgery 69(1):72–78. https://doi.org/10.1227/NEU.0b013e318212badb

    Article  PubMed  Google Scholar 

  10. Stienen MN, Visser-Meily JM, Schweizer TA et al (2019) Prioritization and timing of outcomes and endpoints after aneurysmal subarachnoid hemorrhage in clinical trials and observational studies: proposal of a multidisciplinary research group. Neurocrit Care 30:102–113. https://doi.org/10.1007/s12028-019-00737-0

    Article  PubMed  Google Scholar 

  11. Kazim SF, Ogulnick JV, Robinson MB et al (2021) Cognitive impairment after intracerebral hemorrhage: a systematic review and meta-analysis. World Neurosurg 148:141–162. https://doi.org/10.1016/j.wneu.2021.01.026

    Article  PubMed  Google Scholar 

  12. Armstrong TS, Dirven L, Arons D et al (2020) Glioma patient-reported outcome assessment in clinical care and research: a Response Assessment in Neuro-Oncology collaborative report. Lancet Oncol 21(2):e97–e103. https://doi.org/10.1016/S1470-2045(19)30796-X

    Article  PubMed  Google Scholar 

  13. De Witt Hamer PC, Klein M, Hervey-Jumper SL et al (2021) Functional outcomes and health-related quality of life following glioma surgery. Neurosurgery 88(4):720–732. https://doi.org/10.1093/neuros/nyaa365

    Article  PubMed  PubMed Central  Google Scholar 

  14. Corniola MV, Meling TR (2021) Functional outcome and quality of life after meningioma surgery: a systematic review. Acta Neurol Scand 143(5):467–474. https://doi.org/10.1111/ane.13395

    Article  PubMed  Google Scholar 

  15. Van Coevorden-van Loon EMP, Heijenbrok-Kal MH, Van Loon WS et al (2015) Assessment methods and prevalence of cognitive dysfunction in patients with low-grade glioma: a systematic review. J Rehabil Med 47(6):481–488. https://doi.org/10.2340/16501977-1975

    Article  Google Scholar 

  16. Meskal I, Gehring K, Rutten GJM, Sitskoorn MM (2016) Cognitive functioning in meningioma patients: a systematic review. J Neurooncol 128(2):195–205. https://doi.org/10.1007/s11060-016-2115-z

    Article  PubMed  PubMed Central  Google Scholar 

  17. Andersen CR, Fitzgerald E, Delaney A, Finfer S (2019) A systematic review of outcome measures employed in aneurysmal subarachnoid hemorrhage (aSAH) clinical research. Neurocrit Care 30(3):534–541. https://doi.org/10.1007/s12028-018-0566-0

    Article  PubMed  Google Scholar 

  18. Sumsion T (1998) The Delphi technique: an adaptive research tool. Br J Occup Ther 64(4):153–156. https://doi.org/10.1177/030802269806100403

    Article  Google Scholar 

  19. Butts AM, Weigand S, Brown PD et al (2017) Neurocognition in individuals with incidentally-identified meningioma. J Neurooncol 134:125–132. https://doi.org/10.1007/s11060-017-2495-8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Zamanipoor Najafabadi AH, Peeters MCM, Dirven L et al (2017) Impaired health-related quality of life in meningioma patients - a systematic review. Neuro Oncol 19(7):897–907. https://doi.org/10.1093/neuonc/now250

    Article  PubMed  Google Scholar 

  21. Luckett T, King MT, Butow PN et al (2011) Choosing between the EORTC QLQ-C30 and FACT-G for measuring health-related quality of life in cancer clinical research: issues, evidence and recommendations. Ann Oncol 22(10):2179–2190. https://doi.org/10.1093/annonc/mdq721

    Article  CAS  PubMed  Google Scholar 

  22. Aaronson NK, Ahmedzai S, Bergman B et al (1993) The European organization for research and treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365–376. https://doi.org/10.1093/jnci/85.5.365

    Article  CAS  PubMed  Google Scholar 

  23. Costantini M, Musso M, Viterbori P et al (1999) Detecting psychological distress in cancer patients: validity of the Italian version of the Hospital Anxiety and Depression Scale. Support Care Cancer 7(3):121–127. https://doi.org/10.1007/s005200050241

    Article  CAS  PubMed  Google Scholar 

  24. Langsdale T (1997) Eq-5D: a generic tool for outcomes measurement. PharmacoEcon Outcome News 109(1):3–4. https://doi.org/10.1007/bf03271524

    Article  Google Scholar 

  25. Waggoner J, Carline JD, Durning SJ (2016) Is there a consensus on consensus methodology? Descriptions and recommendations for future consensus research. Acad Med 91(5):663–668. https://doi.org/10.1097/ACM.0000000000001092

    Article  PubMed  Google Scholar 

  26. Schiavolin S, Raggi A, Scaratti C et al (2018) Patients’ reported outcome measures and clinical scales in brain tumor surgery: results from a prospective cohort study. Acta Neurochir (Wien) 160(5):1053–1061. https://doi.org/10.1007/s00701-018-3505-0

    Article  Google Scholar 

  27. Sagberg LM, Drewes C, Jakola AS, Solheim O (2017) Accuracy of operating neurosurgeons’ prediction of functional levels after intracranial tumor surgery. J Neurosurg 126(4):1173–1180. https://doi.org/10.3171/2016.3.JNS152927

    Article  PubMed  Google Scholar 

  28. Reponen E, Tuominen H, Hernesniemi J, Korja M (2015) Patient-reported outcomes in elective cranial neurosurgery. World Neurosurg 84(6):1845–1851. https://doi.org/10.1016/j.wneu.2015.08.007

    Article  PubMed  Google Scholar 

  29. Drewes C, Sagberg ML, Jakola AS et al (2015) Morbidity after intracranial tumor surgery: sensitivity and specificity of retrospective review of medical records compared with patient-reported outcomes at 30 days. J Neurosurg 123:972–977. https://doi.org/10.3171/2015.3.JNS142959

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors thank all the participants for their participation.

Author information

Authors and Affiliations

  1. Neurology, Public Health, Disability Unit, Fondazione IRCSS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy

    Silvia Schiavolin, Arianna Mariniello & Matilde Leonardi

  2. Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

    Morgan Broggi & Paolo Ferroli

  3. Neurosurgery Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

    Giorgia Abete-Fornara

  4. Department of Brain and Behavioural Sciences, University of Pavia, 27100, Pavia, Italy

    Alessandra Bollani, Giulio Palmas G & Gabriella Bottini

  5. Cognitive Neuropsychology Centre, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy

    Alessandra Bollani, Giulio Palmas G, Gabriella Bottini, Matteo Querzola & Pina Scarpa

  6. NeuroMi - Milan Centre for Neuroscience, University of Milano - Bicocca, 20126, Milan, Italy

    Gabriella Bottini

  7. Neurosurgery Department, Humanitas Clinical and Research Hospital, Milan, Rozzano, Italy

    Alessandra Casarotti

  8. Tourette Center, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

    Sara De Michele

  9. Neuropsychology Centre, Neurology Unit, San Gerardo Hospital, Monza, University of Milano - Bicocca, Milan, Italy

    Valeria Isella & Ilaria Mauri

  10. Specialist Rehabilitation Unit, Fondazione Poliambulanza Hospital, Brescia, Italy

    Alessandra Maietti

  11. Clinical Psychology Unit, Neurosurgical Unit - Head and Neck Neuroscience Department, ASST Ovest Milanese, Legnano, Italy

    Valentina Miramonti

  12. Department of Surgery, Neurosurgery Unit, ASST Lariana-S. Anna Hospital, Como, Italy

    Maria Immacolata Orru

  13. Neurosurgery, Department of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123, Brescia, Italy

    Marta Pertichetti

  14. Fondazione Poliambulanza Hospital, Brescia, Italy

    Elisa Pini

  15. Department of Neurosciences - Unit of Neurology - Stroke Unit, Alessandro Manzoni Hospital, Lecco, Italy

    Rossana Regazzoni

  16. Department of Neurosurgery, Azienda Socio Sanitaria Territoriale Cremona, Ospedale Di Cremona, Cremona, Italy

    Sara Subacchi

Authors
  1. Silvia Schiavolin
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  2. Arianna Mariniello
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  3. Morgan Broggi
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  4. Giorgia Abete-Fornara
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  5. Alessandra Bollani
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  6. Giulio Palmas G
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  7. Gabriella Bottini
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  8. Matteo Querzola
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  10. Alessandra Casarotti
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  11. Sara De Michele
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  12. Valeria Isella
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  13. Ilaria Mauri
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  14. Alessandra Maietti
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  15. Valentina Miramonti
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  16. Maria Immacolata Orru
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  17. Marta Pertichetti
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  18. Elisa Pini
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  19. Rossana Regazzoni
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  20. Sara Subacchi
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  21. Paolo Ferroli
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  22. Matilde Leonardi
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Corresponding author

Correspondence to Arianna Mariniello.

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Schiavolin, S., Mariniello, A., Broggi, M. et al. Patient-reported outcome and cognitive measures to be used in vascular and brain tumor surgery: proposal for a minimum set. Neurol Sci 43, 5143–5151 (2022). https://doi.org/10.1007/s10072-022-06162-0

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  • DOI: https://doi.org/10.1007/s10072-022-06162-0

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