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When uncommon and common coalesce: adult onset Still’s disease associated with breast augmentation as part of autoimmune syndrome induced by adjuvants (ASIA)

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Abstract

Adult onset Still’s disease (AOSD) is an uncommon, multisystemic, auto-inflammatory disorder, while breast augmentation is a very common cosmetic procedure. We describe a case in which these two coalesce, AOSD, manifested with pleuritis and pericarditis, developed after breast mammoplasty. The pathogenetic, missing link, behind the development of AOSD following mammoplasty, is thought to be the autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA). We reviewed other cases of AOSD associated with breast mammoplasty published to date and the literature regarding AOSD and ASIA syndrome. The review is followed by a short debate of whether silicone implants should be explanted in similar, future cases.

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Conflict of interest

The authors declare that they have no conflicts of interest.

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Authors and Affiliations

  1. The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel

    A. Dagan & Y. Shoenfeld

  2. Department of Internal Medicine T, Sheba Medical Center, Tel Hashomer, Israel

    A. Dagan, M. Kogan & G. Segal

  3. Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases, Tel-Aviv University, Tel-Aviv, Israel

    Y. Shoenfeld

  4. Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

    G. Segal

Authors
  1. A. Dagan
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  2. M. Kogan
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  3. Y. Shoenfeld
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  4. G. Segal
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Corresponding author

Correspondence to Y. Shoenfeld.

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Dagan, A., Kogan, M., Shoenfeld, Y. et al. When uncommon and common coalesce: adult onset Still’s disease associated with breast augmentation as part of autoimmune syndrome induced by adjuvants (ASIA). Clin Rheumatol 35, 1643–1648 (2016). https://doi.org/10.1007/s10067-015-2869-2

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  • DOI: https://doi.org/10.1007/s10067-015-2869-2

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