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Gingival bleeding as a predictor of handgrip strength—an observational study and a pilot randomized clinical trial

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Abstract

Objective

The aim of this study was to (i) assess the association between self-reported periodontal disease and gingival bleeding as predictors of handgrip strength (HGS) in the elderly and (ii) evaluate the impact of baseline periodontal clinical parameters on the improvement of HGS in trained or non-trained treated periodontitis patients.

Methods

For (i), cross-sectional data from the Brazilian Longitudinal Study of Aging were retrieved and association between HGS (dependent variable) and self-reported gingival bleeding, periodontal disease, and missing teeth was analyzed using multiple linear regressions. For (ii), a pilot study was conducted with 17 patients randomly allocated to two groups—physical training or non-training—and followed for 45 days after subgingival instrumentation. Clinical parameters and HGS were recorded before and after treatment.

Results

The observational study showed a significant association between HGS and tooth loss, edentulism and gingival bleeding. The clinical trial showed that baseline bleeding on probing, but not other parameters, was associated with delta HGS.

Conclusion

Taken together, our findings suggest that gingival bleeding could act as a predictor of handgrip strength and its improvement after non-surgical periodontal therapy.

Clinical relevance

Gingival bleeding, either as self-perceived or clinically detected, may impact handgrip strength, an important marker of muscle frailty and mortality.

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Acknowledgements

The authors would like to thank Dr. Tacito Pessoa de Souza Junior's team, from the Department of Physical Education of UFPR,for their assistance in preparing the training protocol.

Funding

The Paraná State Research Foundation (Fundação Araucária, Curitiba, PR, Brazil) and the National Council for Research and Technological Development (CNPq, Brasília, DF, Brazil) partially funded this study (No. 70/2021).

Author information

Authors and Affiliations

  1. Postgraduate Program in Dentistry, Universidade Federal Do Paraná - UFPR, Curitiba, PR, Brazil

    Joao Victor Schoemberger Roth, Gabriel Guidio Guarenghi, Henrique Meister Valenga & Joao Paulo Steffens

  2. School of Dentistry, Universidade Federal Do Paraná - UFPR, Curitiba, PR, Brazil

    Rafael Milani Ferro

  3. Department of Periodontology, Universidade Federal do Rio Grande do Sul – UFRGS, Porto Alegre, RS, Brazil

    Alex Nogueira Haas

  4. Postgraduate Program in Health and Environment, Universidade da Região de Joinville – UNIVILLE, Joinville, SC, Brazil

    Rodolfo Coelho Prates

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  1. Joao Victor Schoemberger Roth
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Contributions

All authors have made substantial contributions to the conception and design of the study. JR was involved in data interpretation and drafting the manuscript. GG, RF, and HM were involved in data collection and data analysis of the pilot study. AH and RP were involved in the observational study data collection and analysis. JS guided the entire work. All authors agreed on the final version of the manuscript.

Corresponding author

Correspondence to Joao Paulo Steffens.

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Competing interests

The authors declare no competing interests.

Ethical approval

This study was approved by the Institutional Ethics Committee under No. 02621018.4.0000.0102.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interests.

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Roth, J.V.S., Guarenghi, G.G., Ferro, R.M. et al. Gingival bleeding as a predictor of handgrip strength—an observational study and a pilot randomized clinical trial. Clin Oral Invest 28, 109 (2024). https://doi.org/10.1007/s00784-024-05507-7

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