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Complete nucleotide sequence of a novel bovine viral diarrhea virus subtype 1 isolate from Italy

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Abstract

To gain further insight into the genomic features of bovine viral diarrhea virus 1 (BVDV-1) subtypes, we sequenced the complete genome of the BVDV-1 isolate VE/245/12. This is an uncommon subtype that was isolated from a persistently infected animal. Here, we report the complete genome sequence, consisting of 12,295 nucleotides (nt) with an open reading frame of 11,694 nt encoding 3,898 amino acids. Phylogenetic analysis of the full-length genome, 5’-UTR, and Npro region confirmed that the BVDV-1 isolate differed significantly from all of the bovine pestiviruses identified so far, providing evidence for the presence of a distinct novel genetic group.

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References

  1. Schirrmeier H, Strebelow G, Depner K, Hoffmann B, Beer M (2004) Genetic and antigenic characterization of an atypical pestivirus isolate, a putative member of a novel pestivirus species. J Gen Virol 85:3647–3652

    Article  CAS  PubMed  Google Scholar 

  2. Giammarioli M, Ceglie L, Rossi E, Bazzucchi M, Casciari C, Petrini S, De Mia GM (2015) Increased genetic diversity of BVDV-1: recent findings and implications thereof. Virus Genes 50:147–151

    Article  CAS  PubMed  Google Scholar 

  3. Luzzago C, Lauzi S, Ebranati E, Giammarioli M, Moreno A, Cannella V, Masoero L, Canelli E, Guercio A, Caruso C, Ciccozzi M, De Mia GM, Acutis PL, Zehender G, Peletto S (2014) Extended genetic diversity of bovine viral diarrhea virus and frequency of genotypes and subtypes in cattle in Italy between 1995 and 2013. Biomed Res Int 2014:147145. doi: 10.1155/2014/147145

    Google Scholar 

  4. Giammarioli M, Pellegrini C, Casciari C, Rossi E, De Mia GM (2008) Genetic diversity of Bovine viral diarrhea virus 1: Italian isolates clustered in at least seven subgenotypes. J Vet Diagn Investig 20(6):783–788

    Article  Google Scholar 

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Authors and Affiliations

  1. Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche, Perugia, Italy

    Moira Bazzucchi, Monica Giammarioli, Elisabetta Rossi & Gian Mario De Mia

  2. Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Grugliasco, TO, Italy

    Luigi Bertolotti & Sergio Rosati

  3. Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, PD, Italy

    Letizia Ceglie

Authors
  1. Moira Bazzucchi
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  2. Luigi Bertolotti
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  3. Letizia Ceglie
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  4. Monica Giammarioli
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  5. Elisabetta Rossi
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  6. Sergio Rosati
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  7. Gian Mario De Mia
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Corresponding author

Correspondence to Gian Mario De Mia.

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Funding

This study was supported by internal funds of the Istituto Zooprofilattico Sperimentale dell’ Umbria e delle Marche (IZS-UM).

Conflict of interest

The authors declare that they have no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Bazzucchi, M., Bertolotti, L., Ceglie, L. et al. Complete nucleotide sequence of a novel bovine viral diarrhea virus subtype 1 isolate from Italy. Arch Virol 162, 3545–3548 (2017). https://doi.org/10.1007/s00705-017-3486-y

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  • DOI: https://doi.org/10.1007/s00705-017-3486-y

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