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Effects of experimentally induced panic attacks on neuroimmunological markers

  • Biological Psychiatry - Short Communication
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Abstract

Since little is known concerning regulation of immunological parameters in rapid changing psychiatric states like panic attacks, we measured cytokines at different time points in healthy subjects, which underwent experimental panic induction using the CCK-4 paradigm. Apart from a challenge related IL-6 increase, we could not observe any changes of neuroimmunological markers in relation to acute anxiety with regard to time and group. Herein we conducted for the first time a new approach to immunological research in panic disorder, suggesting immune changes are more related to long term disease stress.

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Authors and Affiliations

  1. Department of Psychiatry, Ludwig-Maximilian-University, Nussbaumstr. 7, 80336, Munich, Germany

    L. de la Fontaine, M. J. Schwarz, D. Eser, N. Müller & R. Rupprecht

  2. Klinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität, Nussbaumstr. 7, 80336, Munich, Germany

    M. J. Schwarz

  3. Department of Psychiatry and Psychotherapy, University of Munster, Münster, Germany

    P. Zwanzger

Authors
  1. L. de la Fontaine
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  2. M. J. Schwarz
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  3. D. Eser
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  4. N. Müller
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  5. R. Rupprecht
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  6. P. Zwanzger
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Correspondence to M. J. Schwarz.

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de la Fontaine, L., Schwarz, M.J., Eser, D. et al. Effects of experimentally induced panic attacks on neuroimmunological markers. J Neural Transm 116, 699–702 (2009). https://doi.org/10.1007/s00702-008-0140-6

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  • DOI: https://doi.org/10.1007/s00702-008-0140-6

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