Summary.
We assessed a total range of peripheral thyroid hormone fractions, binding globulins, and thyroid-active antibodies in 37 medication-free, violent or sexual offenders, aged 17–45 years, to describe possible mechanisms involved in the thyroid metabolism of aggressive men. The ratio between T3 and T4 correlated with ratings of psychopathy, indicating increased peripheral deiodination as a biological covariate to callous personality traits. Autoimmune antibodies, hepatic failure, abnormal binding globulins, or substance abuse did not affect the association.
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Soderstrom, H., Forsman, A. Elevated triiodothyronine in psychopathy – possible physiological mechanisms. J Neural Transm 111, 739–744 (2004). https://doi.org/10.1007/s00702-004-0137-8
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DOI: https://doi.org/10.1007/s00702-004-0137-8