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Light-driven nanomotors and micromotors: envisioning new analytical possibilities for bio-sensing

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Abstract

The aim of this conceptual review is to cover recent developments of light-propelled micromotors for analytical (bio)-sensing. Challenges of self-propelled light-driven micromotors in complex (biological) media and potential solutions from material aspects and propulsion mechanism to achieve final analytical detection for in vivo and in vitro applications will be comprehensively covered.

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Abbreviations

CV:

Crystal violet

DOX:

Doxorubicin

FITC:

Fluorescein isothiocyanate

GO:

Graphene oxide

QDs:

Quantum dots

MCF-7:

Michigan Cancer Foundation-7 cancer cell line

MTT:

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide

NIR:

Near infrared

NW:

Nanowire

PCL:

Polycaprolactone

PDMS:

Polydimethylsiloxane

PPy:

Polypyrrole

PVA:

Polyvinyl alcohol

rGO:

Reduced graphene oxide

SEM:

Scanning-electron microscopy

SERS:

Surface enhanced Raman scattering

UV:

Ultraviolet

VIS:

Visible

2D:

Two-dimensional

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Funding

This research was funded by the Spanish Ministry of Economy, Industry and Competitiveness, grant numbers CTQ2017-86441-C2-1-R (A.E) and RYC-2015-17558 co-financed by EU (B.J.S, K.Y); the Community of Madrid, grant numbers TRANSNANOAVANSENS, S2018/NMT-4349 (A.E), and CM/JIN/2019-007 (B.J.S, J. B.F); and the Universidad de Alcalá, grant number CCG19/CC-029 (B.J.S).

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Authors and Affiliations

  1. Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcala, Alcala de Henares, 28871, Madrid, Spain

    Kaisong Yuan, Javier Bujalance-Fernández, Beatriz Jurado-Sánchez & Alberto Escarpa

  2. Institute of Pharmaceutical Analysis, College of Pharmacy, Jinan University, Guangzhou, China

    Kaisong Yuan

  3. Chemical Research Institute “Andrés M. del Río”, University of Alcala, Alcala de Henares, 28871, Madrid, Spain

    Beatriz Jurado-Sánchez & Alberto Escarpa

Authors
  1. Kaisong Yuan
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  2. Javier Bujalance-Fernández
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  3. Beatriz Jurado-Sánchez
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  4. Alberto Escarpa
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Contributions

Conceptualization, K. Y., J. B.F., B. J. S. and A. E.; writing-original draft preparation, K. Y., J. B. F., B. J. S.; writing—review and editing, K. Y., J. B.F., B. J. S. and A. E.; supervision, B. J. S. and A. E.; funding acquisition, B. J. S. and A. E. K. Y. and J. B. F. contributed equally to this review.

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Correspondence to Beatriz Jurado-Sánchez or Alberto Escarpa.

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Yuan, K., Bujalance-Fernández, J., Jurado-Sánchez, B. et al. Light-driven nanomotors and micromotors: envisioning new analytical possibilities for bio-sensing. Microchim Acta 187, 581 (2020). https://doi.org/10.1007/s00604-020-04541-y

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