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Ultrasensitive electrochemical sensing of dopamine using reduced graphene oxide sheets decorated with p-toluenesulfonate-doped polypyrrole/Fe3O4 nanospheres

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Abstract

The authors describe a hybrid nanocomposite consisting of polypyrrole (PPy) nanospheres doped with p-toluenesulfonic acid (p-TSA) and deposited on sheets of reduced graphene oxide (rGO). The rGO sheets oxide were first coated with Fe3O4 particles, and pyrrole was then polymerized on their surface to obtain architecture of the type PPy/Fe3O4/rGO. Addition of p-TSA during polymerization leads to the formation of p-TSA-doped PPy to obtain doped-PPy/Fe3O4/rGO. The resulting nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, FTIR, X-ray diffraction spectrometry and X-ray photoelectron spectroscopy. The nanocomposite was placed on a glassy carbon electrode to give an electrochemical sensor for dopamine (DA) that has a fairly low operational voltage (0.3–0.6 V vs. SCE), a wide linear range (7.0 nM–2.0 μM), a low detection limit (2.33 nM), and good selectivity for DA over ascorbic acid and uric acid. It gave satisfactory results in the determination of DA in spiked samples of urine and serum.

A novel hybrid nanocomposite of p-toluenesulfonate-doped polypyrrole@magnetite nanospheres decorated onto reduced graphene oxide sheets (RGO) was prepared. This nanocomposite was immobilized on a glassy carbon electrode (GCE) to fabricate an electrochemical sensor to determine dopamine (DA)

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Acknowledgments

The authors gratefully acknowledge financial supports from the National Natural Science Foundation of China (No. 21304040), Natural Science Foundation of Gansu Province (1308RJYA027) and Chinese Postdoctoral Funds (2013 M532090). This paper is dedicated to memory of our former tutor, pro. Yanfeng Li, who passed away.

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Authors and Affiliations

  1. State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, College of Resources and Environment, Institute of Biochemical Engineering &Environmental Technology, Lanzhou University, Lanzhou, 730000, China

    Yang Wang, Yun Zhang, Chen Hou & Mingzhu Liu

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  1. Yang Wang
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  3. Chen Hou
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Correspondence to Yun Zhang or Mingzhu Liu.

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Wang, Y., Zhang, Y., Hou, C. et al. Ultrasensitive electrochemical sensing of dopamine using reduced graphene oxide sheets decorated with p-toluenesulfonate-doped polypyrrole/Fe3O4 nanospheres. Microchim Acta 183, 1145–1152 (2016). https://doi.org/10.1007/s00604-016-1742-6

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