
Abbreviations
- AUC:
-
The area under curve
- GDM:
-
Gestational diabetes
- hs-CRP:
-
High sensitive CRP
- OR:
-
Odds ratio
- OTUs:
-
Operational taxonomic units
References
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Le Chatelier E, Nielsen T, Qin J et al (2013) Richness of human gut microbiome correlates with metabolic markers. Nature 500(7464):541–546
Gomez-Arango LF, Barrett HL, McIntyre HD et al (2016) Connections between the gut microbiome and metabolic hormones in early pregnancy in overweight and obese women. Diabetes 65(8):2214–2223
Fugmann M, Breier M, Rottenkolber M et al (2015) The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes. Sci Rep 5:13212. doi:10.1038/srep13212
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Acknowledgements
The study was funded by the Academy of Finland (#258606), State research funding for university-level health research of the Turku University Hospital Expert Responsibility Area, the Päivikki and Sakari Sohlberg Foundation (personal funding for KM) and the Finnish Cultural Foundation (Varsinais-Suomi Regional Fund) (personal funding for KM).
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KM and KL designed the study, TV performed the statistical analyses, KM and KL wrote the first draft of the article and finalized the article. All authors contributed to the interpretation of the results and the writing of the manuscript.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All procedures performed involving human subjects were approved by the Ethics Committee of the Hospital District of Southwest Finland (Permission No. 115/180/2012).
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Informed consent was obtained from all individual participants included in the study.
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Mokkala, K., Houttu, N., Vahlberg, T. et al. Gut microbiota aberrations precede diagnosis of gestational diabetes mellitus. Acta Diabetol 54, 1147–1149 (2017). https://doi.org/10.1007/s00592-017-1056-0
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DOI: https://doi.org/10.1007/s00592-017-1056-0
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