Abstract
Purpose
We sought to describe coping strategies reported by young breast cancer survivors and evaluate the relationship between utilization of specific coping strategies and anxiety in survivorship.
Methods
Participants enrolled in The Young Women’s Breast Cancer Study, a multi-center, cohort of women diagnosed with breast cancer at age ≤ 40 years, completed surveys that assessed demographics, coping strategies (reported at 6-month post-enrollment and 18-month post-diagnosis), and anxiety (2 years post-diagnosis). We used univariable and multivariable logistic regression to examine the relationship between coping strategies and anxiety.
Results
A total of 833 women with stage 0–3 breast cancer were included in the analysis; median age at diagnosis was 37 (range: 17–40) years. Social supports were the most commonly reported coping strategies, with the majority reporting moderate or greater use of emotional support from a partner (90%), parents (78%), other family (79%), and reliance on friends (88%) at both 6 and 18 months. In multivariable analyses, those with moderate or greater reliance on emotional support from other family (odds ratio (OR): 0.37, 95% confidence ratio (CI): 0.22–0.63) at 18 months were less likely to have anxiety at 2 years, while those with moderate or greater reliance on alcohol/drug use (OR: 1.83, 95%CI: 1.12–3.00) and taking care of others (OR: 1.90, 95%CI: 1.04–3.45) to cope were more likely to have anxiety.
Conclusion
Young breast cancer survivors rely heavily on support from family and friends. Our findings underscore the importance of considering patients’ social networks when developing interventions targeting coping in survivorship.
Clinical trial registration number
NCT01468246 (first posted November 9, 2011).
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Data availability
The data are not publicly available as the Institutional Review Board Committee (IRB)-approved research protocol specified that all data must be collected, coded, and stored at the Dana-Farber Cancer Institute and be limited-access and password-protected, in order to protect the identity of respondents. Requests can be made to share data privately. However, any data sharing will require a formal data transfer agreement between the Dana-Farber Cancer Institute and the other party. Requests to this effect should be directed to the corresponding author.
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Acknowledgements
The authors wish to thank Valerie Hope Goldstein for editorial and submission assistance.
Funding
This research was supported by Susan G. Komen (Partridge), the Breast Cancer Research Foundation (Partridge), the Agency for Healthcare Research and Quality K01HS023680 (Rosenberg), and the Harvard Kennedy School Center for Public Leadership’s Zuckerman Fellowship (Krasne). The funding agreement ensured the authors’ independence in designing the study, interpreting the data, writing, and publishing the report.
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M.K, A.H.P., and S.M.R. provided the initial conceptualization for and writing of the original draft of the manuscript. A.H.P. provided funding acquisition for this study. M.K., S.I.G, A.H.P., R.M.T., and S.M.R. had a significant contribution to the conceptualization of the cohort, methodology, and analysis. All authors contributed to review and editing. M.K. and S.M.R. were responsible for the final manuscript edits.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the IRB. The study was approved by the IRBs of Dana-Farber Harvard Cancer Center, and other participating sites (Beth Israel Deaconess Medical Center, Brigham and Women’s Hospital, Brigham and Women’s Faulkner Hospital, Cape Cod Hospital, Lowell General Hospital, Massachusetts General Hospital, Mayo Clinic, Newton-Wellesley Hospital, North Shore Cancer Center Salem, South Shore Hospital, Sunnybrook Health Sciences Centre, and University of Colorado Hospital).
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Informed consent was obtained from all individuals included in the study.
Competing interests
S.M.R. reports grants from the Agency for Healthcare Research and Quality, during the conduct of the study and current grant funding from Pfizer. R.M.T. reports grants from the NIH/NCI, during the conduct of the study. J.P. reports personal fees from GlaxosmithKline (Spouse, employment), grants from Outcomes4Me Inc, personal fees from Athenex, and personal fees from Abbott Labs, outside the submitted work. A.H.P. receives royalties for co-authoring the Breast Cancer Survivorship section of UpToDate. All other authors declare no competing interests.
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Krasne, M., Ruddy, K.J., Poorvu, P.D. et al. Coping strategies and anxiety in young breast cancer survivors. Support Care Cancer 30, 9109–9116 (2022). https://doi.org/10.1007/s00520-022-07325-7
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DOI: https://doi.org/10.1007/s00520-022-07325-7