Abstract
Silica gel high performance thin layer chromatography–densitometry was used to determine the neutral lipid profile in the urine of BALB/c mice experimentally infected with adults of Echinostoma caproni. An approximate 30 worm burden per host induced certain changes in the neutral lipid profile of the mice at 2 to 10 weeks post-infection (PI) relative to the uninfected controls. Infection caused a significant increase (Student’s t test, P < 0.05) in the methyl oleate fraction at 6 and 7 weeks PI relative to the uninfected controls. Neutral lipid profiles of urine may serve as an indicator of experimental infection of echinostomes in mice.
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Acknowledgment
James D. Vasta was supported by a Camille and Henry Dreyfus Foundation Senior Scientist Mentor Program award to J. Sherma and the Lafayette College EXCEL Scholar Program.
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Vasta, J.D., Fried, B. & Sherma, J. High performance thin layer chromatographic analysis of neutral lipids in the urine of BALB/c mice infected with Echinostoma caproni . Parasitol Res 102, 625–629 (2008). https://doi.org/10.1007/s00436-007-0798-y
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DOI: https://doi.org/10.1007/s00436-007-0798-y