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A distinctive epitheliomesenchymal biphasic tumor in the duodenum: the first case of duodenoblastoma?

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Abstract

Epitheliomesenchymal biphasic neoplasms are extremely rare in the duodenum, and most of these are carcinosarcomas. Miettinen et al. (Am J Surg Pathol 33:1370–7, 2009) recently reported three cases of a novel distinctive epitheliomesenchymal biphasic tumor of the stomach in young adults. In view of the resemblance to other childhood blastomas, they proposed to refer to this entity as a gastroblastoma. Since none of the components were sufficiently atypical, the gastroblastoma seemed more comparable to this kind of tumor than carcinosarcomas or other aggressive and malignant biphasic tumors. This report describes a duodenal location of a similar epitheliomesenchymal biphasic tumor in a 22-year-old woman. To our knowledge, this is the first reported case occurring primarily in the duodenum and might be the first case of “duodenoblastoma.”

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Authors and Affiliations

  1. Department of Biopathology, Paoli Calmettes Institut, 232 Bd Sainte Marguerite, 13009, Marseille, France

    F Poizat, L Xerri & G Monges

  2. Department of Surgery, Paoli Calmettes Institut, 232 Bd Sainte Marguerite, 13009, Marseille, France

    C de Chaisemartin & J R Delpero

  3. Department of Endoscopy, Paoli Calmettes Institut, 232 Bd Sainte Marguerite, 13009, Marseille, France

    E Bories

  4. Department of Pathology, Saint Antoine Hospital, 184 rue du Faubourg Saint Antoine, 75571, Paris Cedex 12, Paris, France

    J F Flejou

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  1. F Poizat
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  2. C de Chaisemartin
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  4. J R Delpero
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  5. L Xerri
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  6. J F Flejou
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  7. G Monges
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Correspondence to F Poizat.

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Poizat, F., de Chaisemartin, C., Bories, E. et al. A distinctive epitheliomesenchymal biphasic tumor in the duodenum: the first case of duodenoblastoma?. Virchows Arch 461, 379–383 (2012). https://doi.org/10.1007/s00428-012-1307-y

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  • DOI: https://doi.org/10.1007/s00428-012-1307-y

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