Abstract
Purpose
Poliomyelitis is an infectious disease that can cause total paralysis. Furthermore, poliomyelitis survivors may develop new signs and symptoms, including muscular weakness and fatigue, years after the acute phase of the disease, i.e., post-polio syndrome (PPS). Thus, the objective was to compare the functional exercise capacity during maximal and submaximal exercises among individuals with polio sequelae (without PPS diagnosis), PPS, and a control group.
Methods
Thirty individuals participated in three groups: a control group (CG, n = 10); a group of individuals with polio sequelae but without PPS diagnosis (PG, n = 10); and a PPS group (PPSG, n = 10). All participants underwent (i) a cardiopulmonary exercise test to determine their maximal oxygen uptake (\({\dot{\text{V}}\text{O}}_{{2}} {\text{max}}\)) and (ii) a series of functional field tests (i.e., walking test, sit-to-stand test, and stair climbing test).
Results
\(\dot{V}\)O2max was 30% lower in PPSG than in CG and PG. Regarding functional field tests, walking and stair climbing test performances were significantly different among all groups. The PPSG sit-to-stand performance was lower than CG.
Conclusion
The sequelae of paralytic poliomyelitis impair functional exercise capacity obtained from maximal and submaximal tests, especially in patients with PPS. Furthermore, submaximal variables appear to be more negatively impacted than maximal variables.
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Data availability
The data sets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.
Abbreviations
- ACSM :
-
American College of Sports Medicine
- CG :
-
Control group
- CPET :
-
Cardiopulmonary exercise test
- HR :
-
Heart rate
- PG :
-
Poliomyelitis group
- PPS :
-
Post-poliomyelitis syndrome
- PPSG :
-
Post-polio syndrome group
- RER :
-
Respiratory exchange ratio
- UNIFESP :
-
Universidade Federal de São Paulo
- \(\dot{V}E\) :
-
Minute ventilation
- \(\dot{V}CO_{2}\) :
-
Carbon dioxide uptake
- \(\dot{V}O_{2} max\) :
-
Maximal oxygen uptake
- 6MWT :
-
6-Minute walk test
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Funding
This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001.
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AC. MSA., ASSO., and CABL.: study concept and design; CABL., FCC., and BSS.: data acquisition; AC. and CABL.: data analysis and interpretation; VNO and TGC.: article preparation; CABL.: critical revision of the article. All authors read and approved the final article.
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The present study, the instruments used for data collection, and the analysis of the data were submitted to the ethics committee on Research of the Federal University of São Paulo (UNIFESP), according to the Brazilian Resolution of the National Health Council to experimental procedures with human beings and following the principles of the Declaration of Helsinki. The protocol approval number for this study is 0588/05.
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de Lira, C.A.B., Minozzo, F.C., Costa, T.G. et al. Functional exercise capacity in maximal and submaximal activities of individuals with polio sequelae. Eur J Appl Physiol 123, 711–719 (2023). https://doi.org/10.1007/s00421-022-05095-y
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DOI: https://doi.org/10.1007/s00421-022-05095-y