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Spontaneous remission of vision degrading myodesopsia of posterior vitreous detachment type

  • Retinal Disorders
  • Published:
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Abstract

Purpose

The study aims to observe the spontaneous remission of posterior vitreous detachment (PVD)-type vision degrading myodesopsia (VDM) during long-term follow-up.

Methods

We retrospectively reviewed VDM patients with PVD type that refused any treatment. The ratio and time of significant spontaneous remission of floater symptoms occurring were described. The associated factors with significant remission of floater symptoms were analyzed in the univariate and multivariate logistic regression analyses.

Results

In total, 179 patients with VDM were assessed. The mean age of all patients was 60.56 ± 0.47 years old, and the mean duration of follow-up was 23.89 ± 6.63 months. Of the patients, 40.78% have significant improvement in their floater symptoms after mean 16.55 ± 10.63-month follow-up. Myopia (OR = 0.280, 95% CI = 0.084–0.932, P = 0.038), the number of floaters > 3 (OR = 0.343, 95% CI = 0.172–0.683, P = 0.002), and floaters with string-like pattern (OR = 0.370, 95% CI = 0.166–0.824, P = 0.015) and blocky pattern (OR = 0.299, 95% CI = 0.090–0.993, P = 0.049) were negatively correlated with the significant spontaneous remission of VDM symptoms in the multiple binary logistic regression analysis.

Conclusions

Approximately 40% of VDM patients with PVD may experience significant spontaneous remission during long-term follow-up. Patients that are non-myopic and with fewer floaters are more likely to feel relief from VDM symptoms. Floaters with string-like or blocky patterns are less likely to undergo spontaneous remission.

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Data availability

Raw data will be available upon request.

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Funding

This study was supported in part by the National Science Foundation of Liaoning Province, China (2020-MS-360), and Shenyang Young and Middle-aged Science and Technology Innovation Talent Support Program (RC210267). The funding organization had no role in the design or conduct of this research.

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Author notes

  1. Xing Yang and Cheng Shi contributed equally to this work.

Authors and Affiliations

  1. He Eye Specialist Hospital, No. 128, Huanghe Street, Yuhong District, Shenyang, Liaoning, 110000, China

    Xing Yang, Cheng Shi, Qiang Liu, Emmanuel Eric Pazo & Tiezhu Lin

  2. Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China

    Tiezhu Lin

Authors
  1. Xing Yang
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  2. Cheng Shi
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  3. Qiang Liu
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Contributions

T. Z. L.: research design, interpretation of data, critical revision of the manuscript, and final approval of the version to be published. X. Y., C. S., Q. L.: data acquisition and analysis and drafting the manuscript. E. E. P.: critical revision of the manuscript and data analysis. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Tiezhu Lin.

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All research methods are in accordance with the tenets of the Declaration of Helsinki and approved by the ethics committee Board of the He Eye Specialist Hospital. Written informed consent was waived due to the retrospective design.

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Yang, X., Shi, C., Liu, Q. et al. Spontaneous remission of vision degrading myodesopsia of posterior vitreous detachment type. Graefes Arch Clin Exp Ophthalmol 261, 1571–1577 (2023). https://doi.org/10.1007/s00417-022-05948-4

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  • DOI: https://doi.org/10.1007/s00417-022-05948-4

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