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Post-thyroidectomy bilateral cervical plexus block relieves pain: a systematic review

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Abstract

Purpose

To assess the effectiveness of bilateral superficial cervical plexus block (BSCPB) in treating post-thyroidectomy pain.

Methods

MEDLINE, Embase, Google Scholar, LILACS, and the Cochrane Central Register of Controlled Trials, were extensively searched. The search period extended from 1968 until December 2022. Randomized controlled trials comparing BSCPB to placebo, no block in patients with thyroidectomy for benign or malignant thyroid disease were included. Outcomes were pain in the first 24 h after surgery. Analgesic rescue, period before the first rescue dosage, and 24-h opioid usage were secondary outcomes. The RoB 2 instrument was used to evaluate the risk of bias.

Results

34 of 354 studies were eligible. There were 2,519 patients. BSCPB reduced the intensity of pain postoperatively [SMD: − 1.17 (95% CI: − 1.54 to − 0.81)] and in the first 24 h [− 0.62 (95%: 0.91 to 0.33)]. A considerable delay for the first opioid dose, rescue analgesics, and postoperative opioid usage was also found.

Conclusion

BSCPB’s 24-h analgesic efficacy minimizes the requirement for rescue analgesia, postoperative opioid intake, and rescue analgesia start time. The choice of anesthetic and different application methods might affect its effectiveness.

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Funding

Carlos Betancourt and Alvaro Sanabria declare that no funding was received.

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Authors and Affiliations

  1. Head and Neck Service, Hospital Alma Mater, Medellín, Colombia

    Carlos Betancourt & Alvaro Sanabria

  2. CEXCA, Centro de Excelencia en Enfermedades de Cabeza y Cuello, Medellín, Colombia

    Carlos Betancourt & Alvaro Sanabria

  3. Department of Surgery, School of Medicine, Universidad de Antioquia, Cra. 51d #62-29, Medellín, Colombia

    Alvaro Sanabria

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  1. Carlos Betancourt
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Carlos Betancourt: conceptualization, methodology, validation, investigation, data curation, writing—original draft and writing—review and editing. Alvaro Sanabria: conceptualization, methodology, validation, investigation, data curation, formal analysis, writing—original draft and writing—review and editing.

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Betancourt, C., Sanabria, A. Post-thyroidectomy bilateral cervical plexus block relieves pain: a systematic review. Eur Arch Otorhinolaryngol (2024). https://doi.org/10.1007/s00405-024-08626-9

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